Drug-induced interstitial lung disease caused by olaparib: three case reports and review of the Japanese Adverse Drug Event Report database and literature

Drug-induced interstitial lung disease caused by olaparib: three case reports and review of the Japanese Adverse Drug Event Report database and literature

Abstract Background Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, has demonstrated effectiveness in treating ovarian, breast, and other cancers, particularly those with specific molecular subtypes including, but not limited to, BRCA1/2 mutations. Consequently, its utilization is expecte...

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Bibliographic Details
Main Authors: Hiroshi Ishimoto, Noriho Sakamoto, Takashi Kido, Mutsumi Ozasa, Shin Tsutsui, Mayako Mori, Daichi Setoguchi, Shinnosuke Takemoto, Yasushi Obase, Yuji Ishimatsu, Chiharu Tomonaga, Kanako Matsumoto, Sachiko Morisaki, Kiyonori Miura, Hiroshi Mukae
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Pulmonary Medicine
Subjects:
Olaparib
Drug-induced interstitial lung disease
Hypersensitivity pneumonitis like pattern
Ovarian cancer
PARP inhibitor
Case report
Online Access:https://doi.org/10.1186/s12890-023-02569-3

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