Epidemiologic surveillance of nosocomial infections in a Pediatric Intensive Care Unit of a developing country
<p>Abstract</p> <p>Background</p> <p>Nosocomial Infections (NI) are a frequent and relevant problem. The purpose of this study was to determine the epidemiology of the three most common NI in a Pediatric Intensive Care Unit from a developing country.</p> <p>...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2010-09-01
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| Series: | BMC Pediatrics |
| Online Access: | http://www.biomedcentral.com/1471-2431/10/66 |
| _version_ | 1811286393692880896 |
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| author | Becerra María R Tantaleán José A Suárez Víctor J Alvarado Margarita C Candela Jorge L Urcia Flor C |
| author_facet | Becerra María R Tantaleán José A Suárez Víctor J Alvarado Margarita C Candela Jorge L Urcia Flor C |
| author_sort | Becerra María R |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Nosocomial Infections (NI) are a frequent and relevant problem. The purpose of this study was to determine the epidemiology of the three most common NI in a Pediatric Intensive Care Unit from a developing country.</p> <p>Methods</p> <p>We performed a prospective study in a single Pediatric Intensive Care Unit during 12 months. Children were assessed for 3 NI: bloodstream infections (BSI), ventilator-associated pneumonia (VAP) and urinary tract infections (UTI), according to Center for Disease Control criteria. Use of devices (endotracheal tube [ETT], central venous catheter [CVC] and urinary catheter [UC]) was recorded.</p> <p>Results</p> <p>Four hundred fourteen patients were admitted; 81 patients (19.5%) developed 85 NIs. Density of incidence of BSI, VAP and UTI was 18.1, 7.9 and 5.1/1000 days of use of CVC, ETT and UC respectively. BSI was more common in children with CVCs than in those without CVCs (20% <it>vs</it>. 4.7%, p < 0.05). <it>Candida </it>spp. was the commonest microorganism in BSI (41%), followed by Coagulase-negative <it>Staphylococcus </it>(17%). <it>Pseudomonas </it>(52%) was the most common germ for VAP and <it>Candida </it>(71%) for UTI. The presence of NI was associated with increased mortality (38.2% <it>vs</it>. 20.4% in children without NI; p < 0.001) and the median length of ICU stay (23 <it>vs</it>. 6 days in children without NI; p < 0.001). Children with NI had longer average hospital stay previous to diagnosis of this condition (12.3 <it>vs</it>. 6 days; p < 0.001).</p> <p>Conclusions</p> <p>One of every 5 children acquires an NI in the PICU. Its presence was associated with increased mortality and length of stay. At the same time a longer stay was associated with an increased risk of developing NI.</p> |
| first_indexed | 2024-04-13T02:58:58Z |
| format | Article |
| id | doaj.art-bbc907facc1f4c38973244ac23fb75af |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-04-13T02:58:58Z |
| publishDate | 2010-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-bbc907facc1f4c38973244ac23fb75af2022-12-22T03:05:30ZengBMCBMC Pediatrics1471-24312010-09-011016610.1186/1471-2431-10-66Epidemiologic surveillance of nosocomial infections in a Pediatric Intensive Care Unit of a developing countryBecerra María RTantaleán José ASuárez Víctor JAlvarado Margarita CCandela Jorge LUrcia Flor C<p>Abstract</p> <p>Background</p> <p>Nosocomial Infections (NI) are a frequent and relevant problem. The purpose of this study was to determine the epidemiology of the three most common NI in a Pediatric Intensive Care Unit from a developing country.</p> <p>Methods</p> <p>We performed a prospective study in a single Pediatric Intensive Care Unit during 12 months. Children were assessed for 3 NI: bloodstream infections (BSI), ventilator-associated pneumonia (VAP) and urinary tract infections (UTI), according to Center for Disease Control criteria. Use of devices (endotracheal tube [ETT], central venous catheter [CVC] and urinary catheter [UC]) was recorded.</p> <p>Results</p> <p>Four hundred fourteen patients were admitted; 81 patients (19.5%) developed 85 NIs. Density of incidence of BSI, VAP and UTI was 18.1, 7.9 and 5.1/1000 days of use of CVC, ETT and UC respectively. BSI was more common in children with CVCs than in those without CVCs (20% <it>vs</it>. 4.7%, p < 0.05). <it>Candida </it>spp. was the commonest microorganism in BSI (41%), followed by Coagulase-negative <it>Staphylococcus </it>(17%). <it>Pseudomonas </it>(52%) was the most common germ for VAP and <it>Candida </it>(71%) for UTI. The presence of NI was associated with increased mortality (38.2% <it>vs</it>. 20.4% in children without NI; p < 0.001) and the median length of ICU stay (23 <it>vs</it>. 6 days in children without NI; p < 0.001). Children with NI had longer average hospital stay previous to diagnosis of this condition (12.3 <it>vs</it>. 6 days; p < 0.001).</p> <p>Conclusions</p> <p>One of every 5 children acquires an NI in the PICU. Its presence was associated with increased mortality and length of stay. At the same time a longer stay was associated with an increased risk of developing NI.</p>http://www.biomedcentral.com/1471-2431/10/66 |
| spellingShingle | Becerra María R Tantaleán José A Suárez Víctor J Alvarado Margarita C Candela Jorge L Urcia Flor C Epidemiologic surveillance of nosocomial infections in a Pediatric Intensive Care Unit of a developing country BMC Pediatrics |
| title | Epidemiologic surveillance of nosocomial infections in a Pediatric Intensive Care Unit of a developing country |
| title_full | Epidemiologic surveillance of nosocomial infections in a Pediatric Intensive Care Unit of a developing country |
| title_fullStr | Epidemiologic surveillance of nosocomial infections in a Pediatric Intensive Care Unit of a developing country |
| title_full_unstemmed | Epidemiologic surveillance of nosocomial infections in a Pediatric Intensive Care Unit of a developing country |
| title_short | Epidemiologic surveillance of nosocomial infections in a Pediatric Intensive Care Unit of a developing country |
| title_sort | epidemiologic surveillance of nosocomial infections in a pediatric intensive care unit of a developing country |
| url | http://www.biomedcentral.com/1471-2431/10/66 |
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