Current state of molecular and metabolic strategies for the improvement of L-asparaginase expression in heterologous systems

Current state of molecular and metabolic strategies for the improvement of L-asparaginase expression in heterologous systems

Heterologous expression of L-asparaginase (L-ASNase) has become an important area of research due to its clinical and food industry applications. This review provides a comprehensive overview of the molecular and metabolic strategies that can be used to optimize the expression of L-ASNase in heterol...

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Bibliographic Details
Main Authors:	Nicolás Lefin, Javiera Miranda, Jorge F. Beltrán, Lisandra Herrera Belén, Brian Effer, Adalberto Pessoa, Jorge G. Farias, Mauricio Zamorano
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Series:	Frontiers in Pharmacology
Subjects:	L-asparaginase molecular strategies rational design heterologous expression system industrial bioprocessing
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1208277/full

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