Glomerulonephritis associated with tuberculosis: A case report and literature review
Rapidly progressive glomerulonephritis caused mycobacterium tuberculosis is rare; however, three case have been reported to date. Crescentic glomerulonephritis is a life-threatening disease and together with the presence of tuberculous infection is associated with a poor outcome if treatment is inad...
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| Format: | Article |
| Language: | English |
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Wiley
2013-06-01
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| Series: | Kaohsiung Journal of Medical Sciences |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1607551X12003063 |
| _version_ | 1818274726921895936 |
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| author | Yalcin Solak Abduzhappar Gaipov Melih Anil Huseyin Atalay Orhan Ozbek Kultigin Turkmen Ilker Polat Suleyman Turk |
| author_facet | Yalcin Solak Abduzhappar Gaipov Melih Anil Huseyin Atalay Orhan Ozbek Kultigin Turkmen Ilker Polat Suleyman Turk |
| author_sort | Yalcin Solak |
| collection | DOAJ |
| description | Rapidly progressive glomerulonephritis caused mycobacterium tuberculosis is rare; however, three case have been reported to date. Crescentic glomerulonephritis is a life-threatening disease and together with the presence of tuberculous infection is associated with a poor outcome if treatment is inadequate and delayed. We describe the case of a 31-year-old female patient with nephrotic syndrome and progressive renal failure secondary to pulmonary tuberculosis. Renal biopsy showed crescent formation in 14 out of 27 glomeruli, and there was diffuse linear staining of immunoglobulin G deposits. Treatment included corticosteroids in combination with antituberculosis drugs for 2 months, and resulted in a significant improvement in renal function, the disappearance of proteinuria and pulmonary symptoms. We also present a review of the pertinent literature and discuss the pathophysiology of tuberculosis-related acute postinfectious glomerulonephritis. |
| first_indexed | 2024-12-12T22:18:27Z |
| format | Article |
| id | doaj.art-bbcbd8a4c4484d03b6eabb4bba2c074c |
| institution | Directory Open Access Journal |
| issn | 1607-551X |
| language | English |
| last_indexed | 2024-12-12T22:18:27Z |
| publishDate | 2013-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Kaohsiung Journal of Medical Sciences |
| spelling | doaj.art-bbcbd8a4c4484d03b6eabb4bba2c074c2022-12-22T00:10:00ZengWileyKaohsiung Journal of Medical Sciences1607-551X2013-06-0129633734210.1016/j.kjms.2012.10.008Glomerulonephritis associated with tuberculosis: A case report and literature reviewYalcin Solak0Abduzhappar Gaipov1Melih Anil2Huseyin Atalay3Orhan Ozbek4Kultigin Turkmen5Ilker Polat6Suleyman Turk7Division of Nephrology, Department of Internal Medicine, Meram School of Medicine, Konya University, Meram, Konya, TurkeyDivision of Nephrology, Department of Internal Medicine, Meram School of Medicine, Konya University, Meram, Konya, TurkeyDivision of Nephrology, Department of Internal Medicine, Meram School of Medicine, Konya University, Meram, Konya, TurkeyDivision of Nephrology, Department of Internal Medicine, Meram School of Medicine, Konya University, Meram, Konya, TurkeyDepartment of Radiology, Meram School of Medicine, Konya University, Meram, Konya, TurkeyDivision of Nephrology, Department of Internal Medicine, Meram School of Medicine, Konya University, Meram, Konya, TurkeyDepartment of Internal Medicine, Meram School of Medicine, Konya University, Meram, Konya, TurkeyDivision of Nephrology, Department of Internal Medicine, Meram School of Medicine, Konya University, Meram, Konya, TurkeyRapidly progressive glomerulonephritis caused mycobacterium tuberculosis is rare; however, three case have been reported to date. Crescentic glomerulonephritis is a life-threatening disease and together with the presence of tuberculous infection is associated with a poor outcome if treatment is inadequate and delayed. We describe the case of a 31-year-old female patient with nephrotic syndrome and progressive renal failure secondary to pulmonary tuberculosis. Renal biopsy showed crescent formation in 14 out of 27 glomeruli, and there was diffuse linear staining of immunoglobulin G deposits. Treatment included corticosteroids in combination with antituberculosis drugs for 2 months, and resulted in a significant improvement in renal function, the disappearance of proteinuria and pulmonary symptoms. We also present a review of the pertinent literature and discuss the pathophysiology of tuberculosis-related acute postinfectious glomerulonephritis.http://www.sciencedirect.com/science/article/pii/S1607551X12003063Anti-tuberculosis treatmentCrescentic glomerulonephritisPulmonary tuberculosisRenal failure |
| spellingShingle | Yalcin Solak Abduzhappar Gaipov Melih Anil Huseyin Atalay Orhan Ozbek Kultigin Turkmen Ilker Polat Suleyman Turk Glomerulonephritis associated with tuberculosis: A case report and literature review Kaohsiung Journal of Medical Sciences Anti-tuberculosis treatment Crescentic glomerulonephritis Pulmonary tuberculosis Renal failure |
| title | Glomerulonephritis associated with tuberculosis: A case report and literature review |
| title_full | Glomerulonephritis associated with tuberculosis: A case report and literature review |
| title_fullStr | Glomerulonephritis associated with tuberculosis: A case report and literature review |
| title_full_unstemmed | Glomerulonephritis associated with tuberculosis: A case report and literature review |
| title_short | Glomerulonephritis associated with tuberculosis: A case report and literature review |
| title_sort | glomerulonephritis associated with tuberculosis a case report and literature review |
| topic | Anti-tuberculosis treatment Crescentic glomerulonephritis Pulmonary tuberculosis Renal failure |
| url | http://www.sciencedirect.com/science/article/pii/S1607551X12003063 |
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