Summary: | Background. The causative agent of SARS-CoV-2 coronavirus infection, in addition
to the known effect on the respiratory system, has a pronounced destructive effect on
the vascular bed. The purpose of this study is to evaluate the structural and functional properties
of the large arteries in patients who had undergone COVID-19. Materials and methods.
62 people were examined, who were divided into 2 groups: the first group included 32
healthy volunteers, the second group consisted of 30 people who had suffered COVID-19.
The arterial stiffness was evaluated using the method of applanation tonometry and volume
sphygmography. The local stiffness of the common carotid arteries (CCA) was studied using
the ultrasound with high-frequency RF signal technology. The state of the endothelium
was studied by the method of flow-mediated dilation (FMD). Results. The data obtained in
this study reflect the relationship between the presence of SARS-CoV-2 infection and the
negative change in most parameters reflecting the structural and functional state of the arteries.
Conclusions. By initiating vascular aging earlier, COVID-19 infection has adverse
consequences for the structure and function of the arteries, and, as a consequence, for the
cardiovascular prognosis in those who have been ill.
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