Potential of ultrasound in the evaluation of acute appendicitis during pregnancy: a systematic review and meta-analysis

Objective: To assess the accuracy of ultrasound in diagnosing acute appendicitis in pregnant women. Mechanism: The National Library of Medicine (MEDLINE, 1990–2020), Excerpta Medica Database (EMBASE,1946–2020) and the Cochrane Controlled Trials Register (CENTRAL) were used to extract articles that w...

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Main Authors: Yunlong Li, Shikuan Li
Format: Article
Language:English
Published: IMR Press 2022-01-01
Series:Clinical and Experimental Obstetrics & Gynecology
Subjects:
Online Access:https://www.imrpress.com/journal/CEOG/49/1/10.31083/j.ceog4901015
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author Yunlong Li
Shikuan Li
author_facet Yunlong Li
Shikuan Li
author_sort Yunlong Li
collection DOAJ
description Objective: To assess the accuracy of ultrasound in diagnosing acute appendicitis in pregnant women. Mechanism: The National Library of Medicine (MEDLINE, 1990–2020), Excerpta Medica Database (EMBASE,1946–2020) and the Cochrane Controlled Trials Register (CENTRAL) were used to extract articles that were published in English. A total of five studies involving 521 patients were selected. The DerSimonian and Laird random-effects model and Quality Assessment Tool for Diagnostic Accuracy (QUADAS-2) were used to analyze the data. Findings in brief: We identified 140 related articles and included 5 articles enrolling 521 patients. The values obtained using ultrasound for appendicitis during pregnancy were sensitivity of 0.62 (95% Confidence interval (CI): 0.43–0.78), the specificity of 0.91 (95% CI: 0.74–0.97), and the Positive Likelihood Ratio of 7.0 (95% CI: 2.5–19.7), the Negative Likelihood Ratio of 0.41 (95% CI: 0.27–0.63) and the Diagnostic Odds Ratio of 17 (95% CI : 6–49). Conclusion: Ultrasound had medium-level sensitivity and high specificity for the diagnosis of appendicitis in pregnant women.
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spelling doaj.art-bbd0ade26b5943ae82b04628036696b72022-12-22T03:27:38ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632022-01-014911510.31083/j.ceog4901015S0390-6663(22)01665-7Potential of ultrasound in the evaluation of acute appendicitis during pregnancy: a systematic review and meta-analysisYunlong Li0Shikuan Li1Department of Emergency General Surgery, the Affiliated Hospital of Qingdao University, 266003 Qingdao, Shandong, ChinaDepartment of Emergency General Surgery, the Affiliated Hospital of Qingdao University, 266003 Qingdao, Shandong, ChinaObjective: To assess the accuracy of ultrasound in diagnosing acute appendicitis in pregnant women. Mechanism: The National Library of Medicine (MEDLINE, 1990–2020), Excerpta Medica Database (EMBASE,1946–2020) and the Cochrane Controlled Trials Register (CENTRAL) were used to extract articles that were published in English. A total of five studies involving 521 patients were selected. The DerSimonian and Laird random-effects model and Quality Assessment Tool for Diagnostic Accuracy (QUADAS-2) were used to analyze the data. Findings in brief: We identified 140 related articles and included 5 articles enrolling 521 patients. The values obtained using ultrasound for appendicitis during pregnancy were sensitivity of 0.62 (95% Confidence interval (CI): 0.43–0.78), the specificity of 0.91 (95% CI: 0.74–0.97), and the Positive Likelihood Ratio of 7.0 (95% CI: 2.5–19.7), the Negative Likelihood Ratio of 0.41 (95% CI: 0.27–0.63) and the Diagnostic Odds Ratio of 17 (95% CI : 6–49). Conclusion: Ultrasound had medium-level sensitivity and high specificity for the diagnosis of appendicitis in pregnant women.https://www.imrpress.com/journal/CEOG/49/1/10.31083/j.ceog4901015acute appendicitisultrasounddiagnostic studypregnancymeta-analysis
spellingShingle Yunlong Li
Shikuan Li
Potential of ultrasound in the evaluation of acute appendicitis during pregnancy: a systematic review and meta-analysis
Clinical and Experimental Obstetrics & Gynecology
acute appendicitis
ultrasound
diagnostic study
pregnancy
meta-analysis
title Potential of ultrasound in the evaluation of acute appendicitis during pregnancy: a systematic review and meta-analysis
title_full Potential of ultrasound in the evaluation of acute appendicitis during pregnancy: a systematic review and meta-analysis
title_fullStr Potential of ultrasound in the evaluation of acute appendicitis during pregnancy: a systematic review and meta-analysis
title_full_unstemmed Potential of ultrasound in the evaluation of acute appendicitis during pregnancy: a systematic review and meta-analysis
title_short Potential of ultrasound in the evaluation of acute appendicitis during pregnancy: a systematic review and meta-analysis
title_sort potential of ultrasound in the evaluation of acute appendicitis during pregnancy a systematic review and meta analysis
topic acute appendicitis
ultrasound
diagnostic study
pregnancy
meta-analysis
url https://www.imrpress.com/journal/CEOG/49/1/10.31083/j.ceog4901015
work_keys_str_mv AT yunlongli potentialofultrasoundintheevaluationofacuteappendicitisduringpregnancyasystematicreviewandmetaanalysis
AT shikuanli potentialofultrasoundintheevaluationofacuteappendicitisduringpregnancyasystematicreviewandmetaanalysis