Rethinking the Role of Radiation Therapy in the Management of Epithelial Ovarian Cancer

Radiation has been relegated to a palliative role in the management of epithelial ovarian cancer (EOC). Contemporary radiation techniques, including intensity modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT), and image-guided radiation therapy, enable conformal treatmen...

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Main Authors: Geraldine Jacobson, Valerie Galvan-Turner
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/10/4/211
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author Geraldine Jacobson
Valerie Galvan-Turner
author_facet Geraldine Jacobson
Valerie Galvan-Turner
author_sort Geraldine Jacobson
collection DOAJ
description Radiation has been relegated to a palliative role in the management of epithelial ovarian cancer (EOC). Contemporary radiation techniques, including intensity modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT), and image-guided radiation therapy, enable conformal treatment that controls local disease with minimal morbidity. Recent studies from multiple institutions support the role of radiation in the ablative treatment of oligometastatic disease and control of locally recurrent and metastatic disease. Effective local treatment with radiation complements the role of systemic therapy in the management of EOC; reduces symptoms and disease burden, and may contribute to a prolonged drug free interval.
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spelling doaj.art-bbd2e7ef2b314f52bbec0aa9d9709ffd2023-11-19T21:21:42ZengMDPI AGDiagnostics2075-44182020-04-0110421110.3390/diagnostics10040211Rethinking the Role of Radiation Therapy in the Management of Epithelial Ovarian CancerGeraldine Jacobson0Valerie Galvan-Turner1Department of Radiation Oncology, West Virginia University, Morgantown, WV 26505-9234, USADepartment of Obstetrics and Gynecology, West Virginia University, Morgantown, WV 26505-9234, USARadiation has been relegated to a palliative role in the management of epithelial ovarian cancer (EOC). Contemporary radiation techniques, including intensity modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT), and image-guided radiation therapy, enable conformal treatment that controls local disease with minimal morbidity. Recent studies from multiple institutions support the role of radiation in the ablative treatment of oligometastatic disease and control of locally recurrent and metastatic disease. Effective local treatment with radiation complements the role of systemic therapy in the management of EOC; reduces symptoms and disease burden, and may contribute to a prolonged drug free interval.https://www.mdpi.com/2075-4418/10/4/211ovarian cancerradiation therapystereotactic body radiation (SBRT)
spellingShingle Geraldine Jacobson
Valerie Galvan-Turner
Rethinking the Role of Radiation Therapy in the Management of Epithelial Ovarian Cancer
Diagnostics
ovarian cancer
radiation therapy
stereotactic body radiation (SBRT)
title Rethinking the Role of Radiation Therapy in the Management of Epithelial Ovarian Cancer
title_full Rethinking the Role of Radiation Therapy in the Management of Epithelial Ovarian Cancer
title_fullStr Rethinking the Role of Radiation Therapy in the Management of Epithelial Ovarian Cancer
title_full_unstemmed Rethinking the Role of Radiation Therapy in the Management of Epithelial Ovarian Cancer
title_short Rethinking the Role of Radiation Therapy in the Management of Epithelial Ovarian Cancer
title_sort rethinking the role of radiation therapy in the management of epithelial ovarian cancer
topic ovarian cancer
radiation therapy
stereotactic body radiation (SBRT)
url https://www.mdpi.com/2075-4418/10/4/211
work_keys_str_mv AT geraldinejacobson rethinkingtheroleofradiationtherapyinthemanagementofepithelialovariancancer
AT valeriegalvanturner rethinkingtheroleofradiationtherapyinthemanagementofepithelialovariancancer