Sequence Analysis of In Vivo-Expressed HIV-1 Spliced RNAs Reveals the Usage of New and Unusual Splice Sites by Viruses of Different Subtypes.

Sequence Analysis of In Vivo-Expressed HIV-1 Spliced RNAs Reveals the Usage of New and Unusual Splice Sites by Viruses of Different Subtypes.

HIV-1 RNAs are generated through a complex splicing mechanism, resulting in a great diversity of transcripts, which are classified in three major categories: unspliced, singly spliced (SS), and doubly spliced (DS). Knowledge on HIV-1 RNA splicing in vivo and by non-subtype B viruses is scarce. Here...

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Main Authors: Yolanda Vega, Elena Delgado, Jorge de la Barrera, Cristina Carrera, Ángel Zaballos, Isabel Cuesta, Ana Mariño, Antonio Ocampo, Celia Miralles, Sonia Pérez-Castro, Hortensia Álvarez, Isabel López-Miragaya, Elena García-Bodas, Francisco Díez-Fuertes, Michael M Thomson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4927154?pdf=render

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