Macrophages are necessary for epimorphic regeneration in African spiny mice

Macrophages are necessary for epimorphic regeneration in African spiny mice

How the immune system affects tissue regeneration is not well understood. In this study, we used an emerging mammalian model of epimorphic regeneration, the African spiny mouse, to examine cell-based inflammation and tested the hypothesis that macrophages are necessary for regeneration. By directly...

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Bibliographic Details
Main Authors: Jennifer Simkin, Thomas R Gawriluk, John C Gensel, Ashley W Seifert
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-05-01
Series:eLife
Subjects:
Acomys
epimorphic regeneration
macrophages
inflammation
Online Access:https://elifesciences.org/articles/24623

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