The role of PI3k/AKT signaling pathway in attenuating liver fibrosis: a comprehensive review

The role of PI3k/AKT signaling pathway in attenuating liver fibrosis: a comprehensive review

Excessive accumulation of extracellular matrix (ECM) components within the liver leads to a pathological condition known as liver fibrosis. Alcohol abuse, non-alcoholic fatty liver disease (NAFLD), autoimmune issues, and viral hepatitis cause chronic liver injury. Exploring potential therapeutic tar...

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Bibliographic Details
Main Authors:	Emad Shamsan, Maged Almezgagi, Mohammed Gamah, Naveed Khan, Abdulkareem Qasem, Liu Chuanchuan, Fan Haining
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Series:	Frontiers in Medicine
Subjects:	liver fibrosis attenuating liver fibrosis PI3K/Akt pathway hepatic stellate cells extracellular matrix
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2024.1389329/full

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