Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics
Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of preci...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-42960-6 |
| _version_ | 1797636840264564736 |
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| author | Young Min Park De-Chen Lin |
| author_facet | Young Min Park De-Chen Lin |
| author_sort | Young Min Park |
| collection | DOAJ |
| description | Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of precision diagnostic methods and targeted therapies. |
| first_indexed | 2024-03-11T12:39:55Z |
| format | Article |
| id | doaj.art-bbdad40225414f6889c994fe09d53cc3 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-03-11T12:39:55Z |
| publishDate | 2023-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-bbdad40225414f6889c994fe09d53cc32023-11-05T12:23:02ZengNature PortfolioNature Communications2041-17232023-11-011411310.1038/s41467-023-42960-6Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomicsYoung Min Park0De-Chen Lin1Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, and Norris Comprehensive Cancer Center, University of Southern CaliforniaCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, and Norris Comprehensive Cancer Center, University of Southern CaliforniaSpatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of precision diagnostic methods and targeted therapies.https://doi.org/10.1038/s41467-023-42960-6 |
| spellingShingle | Young Min Park De-Chen Lin Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics Nature Communications |
| title | Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics |
| title_full | Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics |
| title_fullStr | Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics |
| title_full_unstemmed | Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics |
| title_short | Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics |
| title_sort | moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics |
| url | https://doi.org/10.1038/s41467-023-42960-6 |
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