Virological Treatment Monitoring for Chronic Hepatitis B
More than 250 million people worldwide are currently infected with hepatitis B, despite the effectiveness of vaccination and other preventive measures. In terms of treatment, new therapeutic approaches are rapidly developing, promising to achieve the elimination of infected cells and the complete cu...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-06-01
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| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/14/7/1376 |
| _version_ | 1797415136302989312 |
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| author | Elisabetta Loggi Stefano Gitto Filippo Gabrielli Elena Franchi Hajrie Seferi Carmela Cursaro Pietro Andreone |
| author_facet | Elisabetta Loggi Stefano Gitto Filippo Gabrielli Elena Franchi Hajrie Seferi Carmela Cursaro Pietro Andreone |
| author_sort | Elisabetta Loggi |
| collection | DOAJ |
| description | More than 250 million people worldwide are currently infected with hepatitis B, despite the effectiveness of vaccination and other preventive measures. In terms of treatment, new therapeutic approaches are rapidly developing, promising to achieve the elimination of infected cells and the complete cure of infection. The on-treatment monitoring of these innovative antiviral treatments will require the implementation of new virological tools. Therefore, new biomarkers are being evaluated besides the traditional virological and serological assays in order to obtain information on different steps of the viral replication cycle and to monitor response to therapy more accurately. The purpose of this work is to describe both standard and innovative tools for chronic hepatitis B treatment monitoring, and to analyse their potential and feasibility. |
| first_indexed | 2024-03-09T05:44:30Z |
| format | Article |
| id | doaj.art-bbe4fedddb3e46b3bb241ff265cf1b19 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-09T05:44:30Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-bbe4fedddb3e46b3bb241ff265cf1b192023-12-03T12:22:46ZengMDPI AGViruses1999-49152022-06-01147137610.3390/v14071376Virological Treatment Monitoring for Chronic Hepatitis BElisabetta Loggi0Stefano Gitto1Filippo Gabrielli2Elena Franchi3Hajrie Seferi4Carmela Cursaro5Pietro Andreone6Hepatology Unit, Department of Medical & Surgical Sciences, University of Bologna, 40126 Bologna, ItalyDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Florence, ItalyPostgraduate School of Internal Medicine, University of Modena and Reggio Emilia, 41126 Modena, ItalyPostgraduate School of Internal Medicine, University of Modena and Reggio Emilia, 41126 Modena, ItalyPostgraduate School of Internal Medicine, University of Modena and Reggio Emilia, 41126 Modena, ItalyDivision of Internal Medicine, Department of Medical and Surgical Sciences, Maternal-Infantile and Adult, University of Modena and Reggio Emilia, 41126 Modena, ItalyDivision of Internal Medicine, Department of Medical and Surgical Sciences, Maternal-Infantile and Adult, University of Modena and Reggio Emilia, 41126 Modena, ItalyMore than 250 million people worldwide are currently infected with hepatitis B, despite the effectiveness of vaccination and other preventive measures. In terms of treatment, new therapeutic approaches are rapidly developing, promising to achieve the elimination of infected cells and the complete cure of infection. The on-treatment monitoring of these innovative antiviral treatments will require the implementation of new virological tools. Therefore, new biomarkers are being evaluated besides the traditional virological and serological assays in order to obtain information on different steps of the viral replication cycle and to monitor response to therapy more accurately. The purpose of this work is to describe both standard and innovative tools for chronic hepatitis B treatment monitoring, and to analyse their potential and feasibility.https://www.mdpi.com/1999-4915/14/7/1376chronic hepatits Btreatment monitoringserological testsvirological tests |
| spellingShingle | Elisabetta Loggi Stefano Gitto Filippo Gabrielli Elena Franchi Hajrie Seferi Carmela Cursaro Pietro Andreone Virological Treatment Monitoring for Chronic Hepatitis B Viruses chronic hepatits B treatment monitoring serological tests virological tests |
| title | Virological Treatment Monitoring for Chronic Hepatitis B |
| title_full | Virological Treatment Monitoring for Chronic Hepatitis B |
| title_fullStr | Virological Treatment Monitoring for Chronic Hepatitis B |
| title_full_unstemmed | Virological Treatment Monitoring for Chronic Hepatitis B |
| title_short | Virological Treatment Monitoring for Chronic Hepatitis B |
| title_sort | virological treatment monitoring for chronic hepatitis b |
| topic | chronic hepatits B treatment monitoring serological tests virological tests |
| url | https://www.mdpi.com/1999-4915/14/7/1376 |
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