Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient
Mycophenolate mofetil (MMF) is a commonly used immunosuppressive drug in the management of transplant recipients. Gastrointestinal (GI) toxicity (diarrhea) is the most frequently reported adverse event in MMF-treated transplant patients. MMF-induced Graft versus Host Disease has rarely been reported...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=4;spage=506;epage=508;aulast=Patra |
| _version_ | 1819104622044774400 |
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| author | Sushma Patra Mukul Vij B Sukanya Dharmesh Kapoor |
| author_facet | Sushma Patra Mukul Vij B Sukanya Dharmesh Kapoor |
| author_sort | Sushma Patra |
| collection | DOAJ |
| description | Mycophenolate mofetil (MMF) is a commonly used immunosuppressive drug in the management of transplant recipients. Gastrointestinal (GI) toxicity (diarrhea) is the most frequently reported adverse event in MMF-treated transplant patients. MMF-induced Graft versus Host Disease has rarely been reported in literature. We report a case of MMF-induced colitis with Graft versus Host Disease-like features, to highlight the importance of high clinical suspicion for its diagnosis, and that appropriate management in such a setting can reduce morbidity and mortality. We also review the relevant literature. |
| first_indexed | 2024-12-22T02:09:16Z |
| format | Article |
| id | doaj.art-bbe68be25b1c4957baa01b2bb7f7ea84 |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-12-22T02:09:16Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-bbe68be25b1c4957baa01b2bb7f7ea842022-12-21T18:42:27ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292012-01-0155450650810.4103/0377-4929.107792Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipientSushma PatraMukul VijB SukanyaDharmesh KapoorMycophenolate mofetil (MMF) is a commonly used immunosuppressive drug in the management of transplant recipients. Gastrointestinal (GI) toxicity (diarrhea) is the most frequently reported adverse event in MMF-treated transplant patients. MMF-induced Graft versus Host Disease has rarely been reported in literature. We report a case of MMF-induced colitis with Graft versus Host Disease-like features, to highlight the importance of high clinical suspicion for its diagnosis, and that appropriate management in such a setting can reduce morbidity and mortality. We also review the relevant literature.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=4;spage=506;epage=508;aulast=PatraGastrointestinal toxicityliver transplantmycophenolate mofetilMMF-induced colitisgraft versus host disease-like features |
| spellingShingle | Sushma Patra Mukul Vij B Sukanya Dharmesh Kapoor Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient Indian Journal of Pathology and Microbiology Gastrointestinal toxicity liver transplant mycophenolate mofetil MMF-induced colitis graft versus host disease-like features |
| title | Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient |
| title_full | Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient |
| title_fullStr | Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient |
| title_full_unstemmed | Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient |
| title_short | Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient |
| title_sort | mycophenolate mofetil induced colitis with graft versus host disease like features in a liver transplant recipient |
| topic | Gastrointestinal toxicity liver transplant mycophenolate mofetil MMF-induced colitis graft versus host disease-like features |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=4;spage=506;epage=508;aulast=Patra |
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