Vegetative chronic genital herpes with satisfactory response to imiquimod

Abstract Vegetative chronic genital herpes is an atypical presentation of herpes simplex 2 that it is usually seen in patients coinfected with human immunodeficiency virus. Clinically, it is characterized by extensive ulcers that evolve to chronification and hypertrophic pseudotumor forms. Antiviral...

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Main Authors: Stella Meireles Siqueira, Bruna Barroso Gonçalves, Julia Bozetti Loss, Rogerio Ribeiro Estrella
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia 2019-05-01
Series:Anais Brasileiros de Dermatologia
Subjects:
Online Access:http://www.scielo.br/pdf/abd/v94n2/0365-0596-abd-94-02-0221.pdf
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author Stella Meireles Siqueira
Bruna Barroso Gonçalves
Julia Bozetti Loss
Rogerio Ribeiro Estrella
author_facet Stella Meireles Siqueira
Bruna Barroso Gonçalves
Julia Bozetti Loss
Rogerio Ribeiro Estrella
author_sort Stella Meireles Siqueira
collection DOAJ
description Abstract Vegetative chronic genital herpes is an atypical presentation of herpes simplex 2 that it is usually seen in patients coinfected with human immunodeficiency virus. Clinically, it is characterized by extensive ulcers that evolve to chronification and hypertrophic pseudotumor forms. Antiviral drugs are recommended for the treatment, and acyclovir is the most used one. Foscarnet is the treatment of choice to resistant cases, although treatment failure has been reported. We report a male patient, previously diagnosed with human immunodeficiency virus who developed vegetative chronic genital herpes resistant to acyclovir and successfully treated with imiquimod.
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spelling doaj.art-bbe793d912bb45cc89077dc1e08e74ad2022-12-21T21:20:03ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962019-05-0194222122310.1590/abd1806-4841.20198014Vegetative chronic genital herpes with satisfactory response to imiquimodStella Meireles Siqueirahttps://orcid.org/0000-0002-2589-5176Bruna Barroso Gonçalveshttps://orcid.org/0000-0001-5237-6681Julia Bozetti Losshttps://orcid.org/0000-0002-6323-9823Rogerio Ribeiro Estrellahttps://orcid.org/0000-0003-3321-434XAbstract Vegetative chronic genital herpes is an atypical presentation of herpes simplex 2 that it is usually seen in patients coinfected with human immunodeficiency virus. Clinically, it is characterized by extensive ulcers that evolve to chronification and hypertrophic pseudotumor forms. Antiviral drugs are recommended for the treatment, and acyclovir is the most used one. Foscarnet is the treatment of choice to resistant cases, although treatment failure has been reported. We report a male patient, previously diagnosed with human immunodeficiency virus who developed vegetative chronic genital herpes resistant to acyclovir and successfully treated with imiquimod.http://www.scielo.br/pdf/abd/v94n2/0365-0596-abd-94-02-0221.pdfAntiviral agentsDrug therapyEfficacyHerpes genitalisHerpes simplexTherapeutics
spellingShingle Stella Meireles Siqueira
Bruna Barroso Gonçalves
Julia Bozetti Loss
Rogerio Ribeiro Estrella
Vegetative chronic genital herpes with satisfactory response to imiquimod
Anais Brasileiros de Dermatologia
Antiviral agents
Drug therapy
Efficacy
Herpes genitalis
Herpes simplex
Therapeutics
title Vegetative chronic genital herpes with satisfactory response to imiquimod
title_full Vegetative chronic genital herpes with satisfactory response to imiquimod
title_fullStr Vegetative chronic genital herpes with satisfactory response to imiquimod
title_full_unstemmed Vegetative chronic genital herpes with satisfactory response to imiquimod
title_short Vegetative chronic genital herpes with satisfactory response to imiquimod
title_sort vegetative chronic genital herpes with satisfactory response to imiquimod
topic Antiviral agents
Drug therapy
Efficacy
Herpes genitalis
Herpes simplex
Therapeutics
url http://www.scielo.br/pdf/abd/v94n2/0365-0596-abd-94-02-0221.pdf
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AT rogerioribeiroestrella vegetativechronicgenitalherpeswithsatisfactoryresponsetoimiquimod