SDHB Suppresses the Tumorigenesis and Development of ccRCC by Inhibiting Glycolysis

SDHB Suppresses the Tumorigenesis and Development of ccRCC by Inhibiting Glycolysis

Metabolic reprogramming is the prominent feature of clear cell renal cell carcinoma (ccRCC). Succinate dehydrogenase subunit B (SDHB) is one of subunits of mitochondrial respiratory chain complex II. The loss of SDHB function is closely related with metabolic changes in kidney cancer cells. However,...

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Bibliographic Details
Main Authors: Zhiyu Fang, Qiang Sun, Huihui Yang, Junfang Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
SDHB
renal cell carcinoma
prognosis
methylation
glycolysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.639408/full

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