Ondansetron‐induced pseudoallergy with non‐ischemic myocardial injury: A rare case report of Kounis syndrome

Abstract Ondansetron is an FDA‐approved selective serotonin 5‐HT3 receptor commonly indicated as an anti‐emetic agent for nausea and vomiting. It is rare to observe fatal reactions from ondansetron despite having no allergies or previous exposure. We report a case of anaphylactoid reaction with spon...

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Main Authors: Eden Firew, Helen Huang, Ayush Anand, Yonathan Aliye Asfaw, Charmy Parikh, Hamza Rafique Khan
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.6781
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author Eden Firew
Helen Huang
Ayush Anand
Yonathan Aliye Asfaw
Charmy Parikh
Hamza Rafique Khan
author_facet Eden Firew
Helen Huang
Ayush Anand
Yonathan Aliye Asfaw
Charmy Parikh
Hamza Rafique Khan
author_sort Eden Firew
collection DOAJ
description Abstract Ondansetron is an FDA‐approved selective serotonin 5‐HT3 receptor commonly indicated as an anti‐emetic agent for nausea and vomiting. It is rare to observe fatal reactions from ondansetron despite having no allergies or previous exposure. We report a case of anaphylactoid reaction with spontaneous coronary vasospasms in response to intravenous ondansetron.
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spelling doaj.art-bbe990777fea453793d25d0116a042d42023-01-17T04:40:57ZengWileyClinical Case Reports2050-09042022-12-011012n/an/a10.1002/ccr3.6781Ondansetron‐induced pseudoallergy with non‐ischemic myocardial injury: A rare case report of Kounis syndromeEden Firew0Helen Huang1Ayush Anand2Yonathan Aliye Asfaw3Charmy Parikh4Hamza Rafique Khan5American Medical Center Addis Ababa EthiopiaUniversity of Medicine and Health Sciences, Royal College of Surgeons in Ireland Dublin IrelandB. P. Koirala Institute of Health Sciences Dharan NepalInternal Medicine Addis Hiwot Hospital Addis Ababa EthiopiaPramukh Swami Medical College Karamsad IndiaBahawal Victoria Hospital Bahawalpur PakistanAbstract Ondansetron is an FDA‐approved selective serotonin 5‐HT3 receptor commonly indicated as an anti‐emetic agent for nausea and vomiting. It is rare to observe fatal reactions from ondansetron despite having no allergies or previous exposure. We report a case of anaphylactoid reaction with spontaneous coronary vasospasms in response to intravenous ondansetron.https://doi.org/10.1002/ccr3.6781anaphylactoid reactionimmunologyKounis syndromeondansetronspontaneous coronary vasospasms
spellingShingle Eden Firew
Helen Huang
Ayush Anand
Yonathan Aliye Asfaw
Charmy Parikh
Hamza Rafique Khan
Ondansetron‐induced pseudoallergy with non‐ischemic myocardial injury: A rare case report of Kounis syndrome
Clinical Case Reports
anaphylactoid reaction
immunology
Kounis syndrome
ondansetron
spontaneous coronary vasospasms
title Ondansetron‐induced pseudoallergy with non‐ischemic myocardial injury: A rare case report of Kounis syndrome
title_full Ondansetron‐induced pseudoallergy with non‐ischemic myocardial injury: A rare case report of Kounis syndrome
title_fullStr Ondansetron‐induced pseudoallergy with non‐ischemic myocardial injury: A rare case report of Kounis syndrome
title_full_unstemmed Ondansetron‐induced pseudoallergy with non‐ischemic myocardial injury: A rare case report of Kounis syndrome
title_short Ondansetron‐induced pseudoallergy with non‐ischemic myocardial injury: A rare case report of Kounis syndrome
title_sort ondansetron induced pseudoallergy with non ischemic myocardial injury a rare case report of kounis syndrome
topic anaphylactoid reaction
immunology
Kounis syndrome
ondansetron
spontaneous coronary vasospasms
url https://doi.org/10.1002/ccr3.6781
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