Inverted formin 2 regulates intracellular trafficking, placentation, and pregnancy outcome

Inverted formin 2 regulates intracellular trafficking, placentation, and pregnancy outcome

Healthy pregnancy depends on proper placentation—including proliferation, differentiation, and invasion of trophoblast cells—which, if impaired, causes placental ischemia resulting in intrauterine growth restriction and preeclampsia. Mechanisms regulating trophoblast invasion, however, are unknown....

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Bibliographic Details
Main Authors: Katherine Young Bezold Lamm, Maddison L Johnson, Julie Baker Phillips, Michael B Muntifering, Jeanne M James, Helen N Jones, Raymond W Redline, Antonis Rokas, Louis J Muglia
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-01-01
Series:eLife
Subjects:
INF2
extravillous trophoblast invasion
placenta
placental insufficiency
gestational hypertension
intrauterine growth restriction
Online Access:https://elifesciences.org/articles/31150

Internet

https://elifesciences.org/articles/31150

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