Genome-wide tiled detection of circulating Mycobacterium tuberculosis cell-free DNA using Cas13

Genome-wide tiled detection of circulating Mycobacterium tuberculosis cell-free DNA using Cas13

In this work, the authors developed a multiplexed, minimally invasive, CRISPR-Cas13-based approach to detect Mycobacterium tuberculosis cell-free DNA in the plasma of active pulmonary tuberculosis patients.

Bibliographic Details
Main Authors: Sri Gowtham Thakku, Jackson Lirette, Kanagavel Murugesan, Julie Chen, Grant Theron, Niaz Banaei, Paul C. Blainey, James Gomez, Sharon Y. Wong, Deborah T. Hung
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37183-8
Description
Summary:In this work, the authors developed a multiplexed, minimally invasive, CRISPR-Cas13-based approach to detect Mycobacterium tuberculosis cell-free DNA in the plasma of active pulmonary tuberculosis patients.
ISSN:2041-1723

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