Assessment of the Prescriptions of Systemic Antibiotics in Primary Dental Care in Germany from 2017 to 2021: A Longitudinal Drug Utilization Study

(1) Background: Due to increasing antibiotic resistance, the frequency of antibiotic use should be questioned in dentistry and attention paid to the choice of the best suited substance according to guidelines. In Germany, overprescribing of clindamycin was noteworthy in the past. Therefore, the aim...

Full description

Bibliographic Details
Main Authors: Gabriele Gradl, Marita Kieble, Jens Nagaba, Martin Schulz
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/11/12/1723
_version_ 1827642136700387328
author Gabriele Gradl
Marita Kieble
Jens Nagaba
Martin Schulz
author_facet Gabriele Gradl
Marita Kieble
Jens Nagaba
Martin Schulz
author_sort Gabriele Gradl
collection DOAJ
description (1) Background: Due to increasing antibiotic resistance, the frequency of antibiotic use should be questioned in dentistry and attention paid to the choice of the best suited substance according to guidelines. In Germany, overprescribing of clindamycin was noteworthy in the past. Therefore, the aim of our study was to determine the trend of antibiotic prescriptions in primary dental care. (2) Methods: Prescriptions of antibiotics in German primary dental care from 2017 to 2021 were analysed using dispensing data from community pharmacies, claimed to the statutory health insurance (SHI) funds, and compared with all antibiotic prescriptions in primary care. Prescriptions were analysed based on defined daily doses per 1000 SHI-insured persons per day (DID). (3) Results: Amoxicillin was the most frequently prescribed antibiotic (0.505 DID in 2017, 0.627 in 2021, +24.2%) in primary dental care, followed by clindamycin (0.374 DID in 2017, 0.294 in 2021, −21.4%). Dental prescriptions still made up 56% of all clindamycin prescriptions in primary care in 2021. (4) Conclusions: Our study suggests that the problem of overuse of clindamycin in German dentistry has improved, but still persists.
first_indexed 2024-03-09T17:24:20Z
format Article
id doaj.art-bbec2170ac4c49348a5ed5e4481bc411
institution Directory Open Access Journal
issn 2079-6382
language English
last_indexed 2024-03-09T17:24:20Z
publishDate 2022-11-01
publisher MDPI AG
record_format Article
series Antibiotics
spelling doaj.art-bbec2170ac4c49348a5ed5e4481bc4112023-11-24T12:53:16ZengMDPI AGAntibiotics2079-63822022-11-011112172310.3390/antibiotics11121723Assessment of the Prescriptions of Systemic Antibiotics in Primary Dental Care in Germany from 2017 to 2021: A Longitudinal Drug Utilization StudyGabriele Gradl0Marita Kieble1Jens Nagaba2Martin Schulz3German Institute for Drug Use Evaluation (DAPI), 10557 Berlin, GermanyGerman Institute for Drug Use Evaluation (DAPI), 10557 Berlin, GermanyGerman Dental Association (BZÄK), 10115 Berlin, GermanyGerman Institute for Drug Use Evaluation (DAPI), 10557 Berlin, Germany(1) Background: Due to increasing antibiotic resistance, the frequency of antibiotic use should be questioned in dentistry and attention paid to the choice of the best suited substance according to guidelines. In Germany, overprescribing of clindamycin was noteworthy in the past. Therefore, the aim of our study was to determine the trend of antibiotic prescriptions in primary dental care. (2) Methods: Prescriptions of antibiotics in German primary dental care from 2017 to 2021 were analysed using dispensing data from community pharmacies, claimed to the statutory health insurance (SHI) funds, and compared with all antibiotic prescriptions in primary care. Prescriptions were analysed based on defined daily doses per 1000 SHI-insured persons per day (DID). (3) Results: Amoxicillin was the most frequently prescribed antibiotic (0.505 DID in 2017, 0.627 in 2021, +24.2%) in primary dental care, followed by clindamycin (0.374 DID in 2017, 0.294 in 2021, −21.4%). Dental prescriptions still made up 56% of all clindamycin prescriptions in primary care in 2021. (4) Conclusions: Our study suggests that the problem of overuse of clindamycin in German dentistry has improved, but still persists.https://www.mdpi.com/2079-6382/11/12/1723anti-bacterial agentsclindamycindrug utilizationdental careprimary health careinsurance claims analysis
spellingShingle Gabriele Gradl
Marita Kieble
Jens Nagaba
Martin Schulz
Assessment of the Prescriptions of Systemic Antibiotics in Primary Dental Care in Germany from 2017 to 2021: A Longitudinal Drug Utilization Study
Antibiotics
anti-bacterial agents
clindamycin
drug utilization
dental care
primary health care
insurance claims analysis
title Assessment of the Prescriptions of Systemic Antibiotics in Primary Dental Care in Germany from 2017 to 2021: A Longitudinal Drug Utilization Study
title_full Assessment of the Prescriptions of Systemic Antibiotics in Primary Dental Care in Germany from 2017 to 2021: A Longitudinal Drug Utilization Study
title_fullStr Assessment of the Prescriptions of Systemic Antibiotics in Primary Dental Care in Germany from 2017 to 2021: A Longitudinal Drug Utilization Study
title_full_unstemmed Assessment of the Prescriptions of Systemic Antibiotics in Primary Dental Care in Germany from 2017 to 2021: A Longitudinal Drug Utilization Study
title_short Assessment of the Prescriptions of Systemic Antibiotics in Primary Dental Care in Germany from 2017 to 2021: A Longitudinal Drug Utilization Study
title_sort assessment of the prescriptions of systemic antibiotics in primary dental care in germany from 2017 to 2021 a longitudinal drug utilization study
topic anti-bacterial agents
clindamycin
drug utilization
dental care
primary health care
insurance claims analysis
url https://www.mdpi.com/2079-6382/11/12/1723
work_keys_str_mv AT gabrielegradl assessmentoftheprescriptionsofsystemicantibioticsinprimarydentalcareingermanyfrom2017to2021alongitudinaldrugutilizationstudy
AT maritakieble assessmentoftheprescriptionsofsystemicantibioticsinprimarydentalcareingermanyfrom2017to2021alongitudinaldrugutilizationstudy
AT jensnagaba assessmentoftheprescriptionsofsystemicantibioticsinprimarydentalcareingermanyfrom2017to2021alongitudinaldrugutilizationstudy
AT martinschulz assessmentoftheprescriptionsofsystemicantibioticsinprimarydentalcareingermanyfrom2017to2021alongitudinaldrugutilizationstudy