Metabolome and Transcriptome Combinatory Profiling Reveals Fluconazole Resistance Mechanisms of <i>Trichosporon asahii</i> and the Role of Farnesol in Fluconazole Tolerance

Metabolome and Transcriptome Combinatory Profiling Reveals Fluconazole Resistance Mechanisms of <i>Trichosporon asahii</i> and the Role of Farnesol in Fluconazole Tolerance

<i>Trichosporon asahii</i> is a basidiomycete yeast that is pathogenic to humans and animals, and fluconazole-resistant strains have recently increased. Farnesol secreted by fungi is a factor that causes variations in fluconazole resistance; however, few studies have explored the underly...

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Bibliographic Details
Main Authors: Xiaoping Ma, Wanling Yang, Aining Yang, Dong Chen, Chengdong Wang, Shanshan Ling, Sanjie Cao, Zhicai Zuo, Ya Wang, Zhijun Zhong, Guangneng Peng, Ming He, Yu Gu
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Microorganisms
Subjects:
fluconazole resistance
<i>Trichosporon asahii</i>
farnesol
metabolome
transcriptome
Online Access:https://www.mdpi.com/2076-2607/11/11/2798

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