Revisiting Drug Compliance: The Need for a Holistic Approach in the Treatment of Severe Mental Disorders

INTRODUCTION: The limited practice of depot antipsychotics and psychoeducation use, recommended for overcoming the noncompliance of patients with severe mental disorders, is linked to a high incidence of treatment violation. Therefore, the development of personalized mental healthcare approaches is...

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Main Authors: Mikhail Yu. Sorokin, Nikolay G. Neznanov, Natalia B. Lutova, Viktor D. Wied
Format: Article
Language:English
Published: Eco-Vector 2021-11-01
Series:Consortium Psychiatricum
Subjects:
Online Access:https://consortium-psy.com/jour/article/viewFile/93/pdf
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author Mikhail Yu. Sorokin
Nikolay G. Neznanov
Natalia B. Lutova
Viktor D. Wied
author_facet Mikhail Yu. Sorokin
Nikolay G. Neznanov
Natalia B. Lutova
Viktor D. Wied
author_sort Mikhail Yu. Sorokin
collection DOAJ
description INTRODUCTION: The limited practice of depot antipsychotics and psychoeducation use, recommended for overcoming the noncompliance of patients with severe mental disorders, is linked to a high incidence of treatment violation. Therefore, the development of personalized mental healthcare approaches is a crucial healthcare task. AIM: To describe and differentiate the role of clinical, social and psychological factors that lead to different level of treatment engagement of psychiatric inpatients. METHODS: Secondary analysis of findings from 91 inpatients, based on the Treatment Motivation Assessment Questionnaire and Medication Compliance Scale, as well as the Scale of Internalized Stigma of Mental Illness and Perceived Discrimination and Devaluation Scale. Factorial analysis, cluster analysis and analysis of variance with p-level=0.05 and the calculation of the effect size (ES) according to Cohens d and Cramers V were used. RESULTS: The nature of therapy compliance in various categories of patients is mediated differentially, including: the severity of negative symptoms (ES=0.29), the global level of functioning and work maladjustment (ES=0.230.26), various motivational and behavioral styles (ES0.74) and the intensity of psychiatric stigmatization (ES0.88). CONCLUSIONS: Consideration of the clinical, social and psychological factors should empirically determine the strategies for the personalized use of prolonged antipsychotics and socio-psychotherapeutic interventions when developing an individual treatment plan for psychiatric in-patients.
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spelling doaj.art-bbfe53c7b01e4c47a375b25b1baac65d2022-12-22T04:13:04ZengEco-VectorConsortium Psychiatricum2712-76722713-29192021-11-0123172510.17816/CP9347Revisiting Drug Compliance: The Need for a Holistic Approach in the Treatment of Severe Mental DisordersMikhail Yu. Sorokin0https://orcid.org/0000-0003-2502-6365Nikolay G. Neznanov1https://orcid.org/0000-0001-5618-4206Natalia B. Lutova2https://orcid.org/0000-0002-9481-7411Viktor D. Wied3https://orcid.org/0000-0001-7334-2165V.M. Bekhterev National Medical Research Center of Psychiatry and NeurologyV.M. Bekhterev National Medical Research Center of Psychiatry and NeurologyV.M. Bekhterev National Medical Research Center of Psychiatry and NeurologyV.M. Bekhterev National Medical Research Center of Psychiatry and NeurologyINTRODUCTION: The limited practice of depot antipsychotics and psychoeducation use, recommended for overcoming the noncompliance of patients with severe mental disorders, is linked to a high incidence of treatment violation. Therefore, the development of personalized mental healthcare approaches is a crucial healthcare task. AIM: To describe and differentiate the role of clinical, social and psychological factors that lead to different level of treatment engagement of psychiatric inpatients. METHODS: Secondary analysis of findings from 91 inpatients, based on the Treatment Motivation Assessment Questionnaire and Medication Compliance Scale, as well as the Scale of Internalized Stigma of Mental Illness and Perceived Discrimination and Devaluation Scale. Factorial analysis, cluster analysis and analysis of variance with p-level=0.05 and the calculation of the effect size (ES) according to Cohens d and Cramers V were used. RESULTS: The nature of therapy compliance in various categories of patients is mediated differentially, including: the severity of negative symptoms (ES=0.29), the global level of functioning and work maladjustment (ES=0.230.26), various motivational and behavioral styles (ES0.74) and the intensity of psychiatric stigmatization (ES0.88). CONCLUSIONS: Consideration of the clinical, social and psychological factors should empirically determine the strategies for the personalized use of prolonged antipsychotics and socio-psychotherapeutic interventions when developing an individual treatment plan for psychiatric in-patients.https://consortium-psy.com/jour/article/viewFile/93/pdftreatment adherence and compliancepatient engagementmotivationmental disordersstigma
spellingShingle Mikhail Yu. Sorokin
Nikolay G. Neznanov
Natalia B. Lutova
Viktor D. Wied
Revisiting Drug Compliance: The Need for a Holistic Approach in the Treatment of Severe Mental Disorders
Consortium Psychiatricum
treatment adherence and compliance
patient engagement
motivation
mental disorders
stigma
title Revisiting Drug Compliance: The Need for a Holistic Approach in the Treatment of Severe Mental Disorders
title_full Revisiting Drug Compliance: The Need for a Holistic Approach in the Treatment of Severe Mental Disorders
title_fullStr Revisiting Drug Compliance: The Need for a Holistic Approach in the Treatment of Severe Mental Disorders
title_full_unstemmed Revisiting Drug Compliance: The Need for a Holistic Approach in the Treatment of Severe Mental Disorders
title_short Revisiting Drug Compliance: The Need for a Holistic Approach in the Treatment of Severe Mental Disorders
title_sort revisiting drug compliance the need for a holistic approach in the treatment of severe mental disorders
topic treatment adherence and compliance
patient engagement
motivation
mental disorders
stigma
url https://consortium-psy.com/jour/article/viewFile/93/pdf
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