Renal Reperfusion Lesion in Patients with Postrenal Obstruction

Objective: to define a role of renal reperfusion lesion in the development of renal failure in cancer patients after elimination of longstanding urinary tract occlusion.Subjects and methods. The study covered 26 patients in whom cancer disease was complicated by the development of urinary tract obst...

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Main Authors: Yu. S. Sidorenko, N. D. Ushakova, A. A. Maslov, A. V. Yashkina
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2007-12-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/904
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author Yu. S. Sidorenko
N. D. Ushakova
A. A. Maslov
A. V. Yashkina
author_facet Yu. S. Sidorenko
N. D. Ushakova
A. A. Maslov
A. V. Yashkina
author_sort Yu. S. Sidorenko
collection DOAJ
description Objective: to define a role of renal reperfusion lesion in the development of renal failure in cancer patients after elimination of longstanding urinary tract occlusion.Subjects and methods. The study covered 26 patients in whom cancer disease was complicated by the development of urinary tract obstruction with evolving renal failure. All the patients received surgical treatment aimed at eliminating urinary tract occlusion. In the early postoperative period, progression of renal dysfunction was seen in all cases. The time course of changes in microcirculation, gas exchange, oxidative-antioxidative balance, and renal function were investigated to study the mechanisms responsible for the development of renal failure after surgery. Clinical and laboratory indices were analyzed before and 1 and 2 days after surgery.Results. The study has revealed that renal reperfusion lesion plays a prominent role in the development of renal failure in cancer patients after elimination of longstanding urinary tract obstruction, which should be borne in mind when preparing patients for surgery and managing them in the postoperative period, namely, to include membrane-stabilizers, antioxidants, and detoxicant therapy.
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spelling doaj.art-bbfe6e87cafe45a5bfbf10922129847b2023-03-13T09:32:48ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102007-12-013616416710.15360/1813-9779-2007-6-164-167904Renal Reperfusion Lesion in Patients with Postrenal ObstructionYu. S. Sidorenko0N. D. Ushakova1A. A. Maslov2A. V. Yashkina3ФГУ Ростовский научно!исследовательский онкологический институтФГУ Ростовский научно!исследовательский онкологический институтФГУ Ростовский научно!исследовательский онкологический институтФГУ Ростовский научно!исследовательский онкологический институтObjective: to define a role of renal reperfusion lesion in the development of renal failure in cancer patients after elimination of longstanding urinary tract occlusion.Subjects and methods. The study covered 26 patients in whom cancer disease was complicated by the development of urinary tract obstruction with evolving renal failure. All the patients received surgical treatment aimed at eliminating urinary tract occlusion. In the early postoperative period, progression of renal dysfunction was seen in all cases. The time course of changes in microcirculation, gas exchange, oxidative-antioxidative balance, and renal function were investigated to study the mechanisms responsible for the development of renal failure after surgery. Clinical and laboratory indices were analyzed before and 1 and 2 days after surgery.Results. The study has revealed that renal reperfusion lesion plays a prominent role in the development of renal failure in cancer patients after elimination of longstanding urinary tract obstruction, which should be borne in mind when preparing patients for surgery and managing them in the postoperative period, namely, to include membrane-stabilizers, antioxidants, and detoxicant therapy.https://www.reanimatology.com/rmt/article/view/904почечная недостаточностьобструкция мочевых путейопухоли
spellingShingle Yu. S. Sidorenko
N. D. Ushakova
A. A. Maslov
A. V. Yashkina
Renal Reperfusion Lesion in Patients with Postrenal Obstruction
Общая реаниматология
почечная недостаточность
обструкция мочевых путей
опухоли
title Renal Reperfusion Lesion in Patients with Postrenal Obstruction
title_full Renal Reperfusion Lesion in Patients with Postrenal Obstruction
title_fullStr Renal Reperfusion Lesion in Patients with Postrenal Obstruction
title_full_unstemmed Renal Reperfusion Lesion in Patients with Postrenal Obstruction
title_short Renal Reperfusion Lesion in Patients with Postrenal Obstruction
title_sort renal reperfusion lesion in patients with postrenal obstruction
topic почечная недостаточность
обструкция мочевых путей
опухоли
url https://www.reanimatology.com/rmt/article/view/904
work_keys_str_mv AT yussidorenko renalreperfusionlesioninpatientswithpostrenalobstruction
AT ndushakova renalreperfusionlesioninpatientswithpostrenalobstruction
AT aamaslov renalreperfusionlesioninpatientswithpostrenalobstruction
AT avyashkina renalreperfusionlesioninpatientswithpostrenalobstruction