Replicability analysis in genome-wide association studies via Cartesian hidden Markov models

Abstract Background Replicability analysis which aims to detect replicated signals attracts more and more attentions in modern scientific applications. For example, in genome-wide association studies (GWAS), it would be of convincing to detect an association which can be replicated in more than one...

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Bibliographic Details
Main Authors: Pengfei Wang, Wensheng Zhu
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-019-2707-7