Upregulation of Slug expression by cyclosporine A contributes to the pathogenesis of gingival overgrowth

Upregulation of Slug expression by cyclosporine A contributes to the pathogenesis of gingival overgrowth

Gingival overgrowth occurs as a side effect of systemic medication with immunosuppressant cyclosporine A (CsA). Slug, a master regulator of epithelial–mesenchymal transition, is dramatically upregulated in a variety of fibrotic diseases. The aim of this study is to investigate the role of epithelial...

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Bibliographic Details
Main Authors: Chung-Hung Tsai, Cheng-Chia Yu, Shiuan-Shinn Lee, Hui-Chieh Yu, Fu-Mei Huang, Yu-Chao Chang
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Journal of the Formosan Medical Association
Subjects:
cyclosporine A
epithelial–mesenchymal transition
gingival overgrowth
Slug
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664616300766

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