Circulating immune checkpoints predict heart failure outcomes

Circulating immune checkpoints predict heart failure outcomes

Abstract Aims There are limited data examining the role of immune checkpoint (IC) ligands in the pathophysiology of heart failure (HF). Therefore, we explore this in three HF animal models and in three different human cohorts (healthy, stable, and worsening HF). Methods and results Transcriptomic an...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Elles M. Screever, Laura I.E. Yousif, Javid J. Moslehi, Joe‐Elie Salem, Adriaan A. Voors, Herman H.W. Silljé, Rudolf A. deBoer, Wouter C. Meijers
Μορφή:	Άρθρο
Γλώσσα:	English
Έκδοση:	Wiley 2023-08-01
Σειρά:	ESC Heart Failure
Θέματα:	Immune checkpoints PD‐L1 PD‐L2 Galectin‐9 Heart failure
Διαθέσιμο Online:	https://doi.org/10.1002/ehf2.14304

Παρόμοια τεκμήρια

Neurologic toxicity associated with immune checkpoint inhibitors: a pharmacovigilance study
ανά: Douglas B. Johnson, κ.ά.
Έκδοση: (2019-05-01)

Checkpoint Inhibition in Myeloma: Opportunities and Challenges
ανά: Federica Costa, κ.ά.
Έκδοση: (2018-09-01)

The role of immune checkpoints in cardiovascular disease
ανά: Laura I. Yousif, κ.ά.
Έκδοση: (2022-10-01)

Enhancing cancer care with improved checkpoint inhibitors
ανά: Vickram A S, κ.ά.
Έκδοση: (2024-10-01)

Checkmate with checkpoint inhibitors: New paradigm in immunotherapy
ανά: Ruby Dhar, κ.ά.
Έκδοση: (2023-04-01)

Characterization of PD-1/PD-L1 Immune Checkpoint Expression in Osteosarcoma
ανά: Kazuhiko Hashimoto, κ.ά.
Έκδοση: (2020-07-01)

Immune Checkpoint in Glioblastoma: Promising and Challenging
ανά: Jing Huang, κ.ά.
Έκδοση: (2017-05-01)

Phytochemicals in Cancer Immune Checkpoint Inhibitor Therapy
ανά: Juwon Lee, κ.ά.
Έκδοση: (2021-07-01)

Overview of the Cardiotoxicity Induced by PD-1/PD-L1 Immune Checkpoint Inhibitor in Critical Care
ανά: Ruiting Li, κ.ά.
Έκδοση: (2021-06-01)

On Demand Biosensors for Early Diagnosis of Cancer and Immune Checkpoints Blockade Therapy Monitoring from Liquid Biopsy
ανά: Sai Mummareddy, κ.ά.
Έκδοση: (2021-12-01)

PD-1/PD-L1 immune checkpoint inhibitors in glioblastoma: clinical studies, challenges and potential
ανά: Tianrui Yang, κ.ά.
Έκδοση: (2021-02-01)

PD-L1 expression on malignant cells is no prerequisite for checkpoint therapy
ανά: Jan Willem Kleinovink, κ.ά.
Έκδοση: (2017-04-01)

Epigenetic modifications of the immune-checkpoint genes CTLA4 and PDCD1 in non-small cell lung cancer results in increased expression
ανά: Sebastian Marwitz, κ.ά.
Έκδοση: (2017-05-01)

Immune Checkpoint Inhibitors in Cancer Therapy
ανά: Yavar Shiravand, κ.ά.
Έκδοση: (2022-04-01)

Research Progress on Cardiotoxicity of PD-1/PD-L1 Immune Checkpoint Inhibitors
ανά: YU Lin, κ.ά.
Έκδοση: (2021-08-01)

The Role of Immune Checkpoint Inhibitors in Cancer Therapy
ανά: Ahmed M. Basudan
Έκδοση: (2022-12-01)

The role of immune checkpoint inhibitors in prostate cancer
ανά: Gabriel Surdacki, κ.ά.
Έκδοση: (2019-03-01)

Editorial: The Roles of Checkpoint Inhibitors in Inflammatory Diseases
ανά: Andreas von Knethen, κ.ά.
Έκδοση: (2021-10-01)

Activity and Safety of Immune Checkpoint Inhibitors in Neuroendocrine Neoplasms: A Systematic Review and Meta-Analysis
ανά: Alberto Bongiovanni, κ.ά.
Έκδοση: (2021-05-01)

Predictive Biomarkers of Immune Checkpoint Inhibitors-Related Toxicities
ανά: Ya Xu, κ.ά.
Έκδοση: (2020-10-01)

Structural Characterization of a Macrocyclic Peptide Modulator of the PD-1/PD-L1 Immune Checkpoint Axis
ανά: Edyta Zyla, κ.ά.
Έκδοση: (2021-08-01)

The Neonatal Innate Immune Response to Sepsis: Checkpoint Proteins as Novel Mediators of This Response and as Possible Therapeutic/Diagnostic Levers
ανά: Emily Hensler, κ.ά.
Έκδοση: (2022-07-01)

Key questions about the checkpoint blockade-are microRNAs an answer?
ανά: Mihnea Dragomir, κ.ά.
Έκδοση: (2018-06-01)

Vascular Targeting to Increase the Efficiency of Immune Checkpoint Blockade in Cancer
ανά: Maria Georganaki, κ.ά.
Έκδοση: (2018-12-01)

Enhancement of anti-tumor efficacy of immune checkpoint blockade by alpha-TEA
ανά: William L. Redmond, κ.ά.
Έκδοση: (2023-02-01)

The epigenetic immunomodulator, HBI-8000, enhances the response and reverses resistance to checkpoint inhibitors
ανά: Reid P. Bissonnette, κ.ά.
Έκδοση: (2021-08-01)

Advances in immune checkpoint inhibitors for hepatocellular carcinoma
ανά: Ji Won Han, κ.ά.
Έκδοση: (2021-09-01)

Immune Checkpoint Inhibitors: Ctla-4 and Pd-1/Pd-l1 in Immunotherapy
ανά: Kübra KAHVECİ, κ.ά.
Έκδοση: (2019-12-01)

Radiation, Immune Checkpoint Blockade and the Abscopal Effect: A Critical Review on Timing, Dose and Fractionation
ανά: Zachary S. Buchwald, κ.ά.
Έκδοση: (2018-12-01)

Safety and efficacy of PD-1/PD-L1 immune checkpoint inhibitors in patients with pre-treated advanced stage malignant mesothelioma: a systematic review and meta-analysis
ανά: Amjad Zafar, κ.ά.
Έκδοση: (2024-11-01)

The impact of antibiotic use on clinical features and survival outcomes of cancer patients treated with immune checkpoint inhibitors
ανά: Jiaxin Zhou, κ.ά.
Έκδοση: (2022-07-01)

Tumor immunotherapies by immune checkpoint inhibitors (ICIs); the pros and cons
ανά: Adel Naimi, κ.ά.
Έκδοση: (2022-04-01)

Editorial: Biomarkers of Immune-Checkpoint-Inhibitor Immunotherapies in Hepatocellular Carcinomas
ανά: Zhanjun Guo, κ.ά.
Έκδοση: (2022-03-01)

Profiling targetable immune checkpoints in osteosarcoma
ανά: Troy A McEachron, κ.ά.
Έκδοση: (2018-12-01)

The Use of Phytochemicals to Improve the Efficacy of Immune Checkpoint Inhibitors: Opportunities and Challenges
ανά: Deniz Can Guven, κ.ά.
Έκδοση: (2022-10-01)

Commentary: Chronic PD-1 Checkpoint Blockade Does Not Affect Cognition or Promote Tau Clearance in a Tauopathy Mouse Model
ανά: Kuti Baruch, κ.ά.
Έκδοση: (2020-05-01)

NSCLC: from tumorigenesis, immune checkpoint misuse to current and future targeted therapy
ανά: Leona Raskova Kafkova, κ.ά.
Έκδοση: (2024-02-01)

Efficacy and safety of immune checkpoint inhibitors in non-small cell lung cancer
ανά: Shuai Wang, κ.ά.
Έκδοση: (2018-08-01)

PD/1-PD-Ls Checkpoint: Insight on the Potential Role of NK Cells
ανά: Silvia Pesce, κ.ά.
Έκδοση: (2019-06-01)

In Search of Better Peptide-(Derived from PD-L2)-Based Immune Checkpoint Inhibitors
ανά: Boris Klebansky, κ.ά.
Έκδοση: (2024-05-01)