Circulating immune checkpoints predict heart failure outcomes

Circulating immune checkpoints predict heart failure outcomes

Abstract Aims There are limited data examining the role of immune checkpoint (IC) ligands in the pathophysiology of heart failure (HF). Therefore, we explore this in three HF animal models and in three different human cohorts (healthy, stable, and worsening HF). Methods and results Transcriptomic an...

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Bibliographic Details
Main Authors: Elles M. Screever, Laura I.E. Yousif, Javid J. Moslehi, Joe‐Elie Salem, Adriaan A. Voors, Herman H.W. Silljé, Rudolf A. deBoer, Wouter C. Meijers
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:ESC Heart Failure
Subjects:
Immune checkpoints
PD‐L1
PD‐L2
Galectin‐9
Heart failure
Online Access:https://doi.org/10.1002/ehf2.14304

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