Circulating immune checkpoints predict heart failure outcomes

Circulating immune checkpoints predict heart failure outcomes

Abstract Aims There are limited data examining the role of immune checkpoint (IC) ligands in the pathophysiology of heart failure (HF). Therefore, we explore this in three HF animal models and in three different human cohorts (healthy, stable, and worsening HF). Methods and results Transcriptomic an...

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Detalles Bibliográficos
Main Authors: Elles M. Screever, Laura I.E. Yousif, Javid J. Moslehi, Joe‐Elie Salem, Adriaan A. Voors, Herman H.W. Silljé, Rudolf A. deBoer, Wouter C. Meijers
Formato: Artigo
Idioma:English
Publicado: Wiley 2023-08-01
Series:ESC Heart Failure
Subjects:
Immune checkpoints
PD‐L1
PD‐L2
Galectin‐9
Heart failure
Acceso en liña:https://doi.org/10.1002/ehf2.14304

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