Successful expansion of Mycobacterium tuberculosis Latin American and Mediterranean sublineage (L4.3/LAM) in Tunisia mainly driven by a single, long-established clonal complex

Successful expansion of Mycobacterium tuberculosis Latin American and Mediterranean sublineage (L4.3/LAM) in Tunisia mainly driven by a single, long-established clonal complex

Objectives: To explore the evolutionary history of Mycobacterium tuberculosis Latin American and Mediterranean (L4.3/LAM) sublineage in Tunisia, where it predominates. Methods: High-resolution genotyping of 252 L4.3/LAM clinical strains was undertaken, and whole-genome sequencing was performed on 31...

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Bibliographic Details
Main Authors: Mohamed Amine Skhairia, Naira Dekhil, Besma Mhenni, Saloua Ben Fradj, Helmi Mardassi
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:International Journal of Infectious Diseases
Subjects:
Mycobacterium tuberculosis
L4.3/LAM
Genotyping
Clonal complex
Whole-genome sequencing
Evolution
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971220325108

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