Theileria annulata Induced Bilateral Ocular Signs in Cattle and its Successful Therapeutic Management: A Case Report
Bovine tropical theileriosis is one of the potentially fatal disease of dairy cattle, which is caused by hemoparasite Theleria annulata. About seven years old cross-bred cow was presented with complaint of pyrexia, inappetance, lacrimation and ocular swelling since last 5 days. The clinical examina...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2023-09-01
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| Series: | Iranian Journal of Parasitology |
| Subjects: | |
| Online Access: | https://ijpa.tums.ac.ir/index.php/ijpa/article/view/3843 |
| _version_ | 1827808069128552448 |
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| author | Anil Kumar Pankaj Kumar Sonam Bhatt Ajeet Kumar G.D Singh Ankesh Kumar |
| author_facet | Anil Kumar Pankaj Kumar Sonam Bhatt Ajeet Kumar G.D Singh Ankesh Kumar |
| author_sort | Anil Kumar |
| collection | DOAJ |
| description |
Bovine tropical theileriosis is one of the potentially fatal disease of dairy cattle, which is caused by hemoparasite Theleria annulata. About seven years old cross-bred cow was presented with complaint of pyrexia, inappetance, lacrimation and ocular swelling since last 5 days. The clinical examination showed elevated rectal temperature (39.4 0C), mild enlarged pre-scapular lymph nodes, bilateral bulging of temporal fossa, protruded pale and icteric conjunctivae of the eyes with lacrimation and presence of ticks on body. The case was suspected for haemoprotozoan disease. Blood and serum sample were collected for hematological, blood smear examination and molecular examination (PCR), and biochemical analysis respectively. Microscopic examination of blood smear revealed intra-erythrocytic signet ring shaped periplasm of Theileria annulata. Hemato-biochemical examination revealed anemia, hypoproteinemia, hypoalbuminemia and jaundice. Further, PCR assay was done using T. annulata-specific primer pair, Cyto b1 gene targeting the amplicon of 312 bp showed specific band on Gel-electrophoresis. Therapeutic regimen was started with Buparvaquone @ 2.5 mg/kg body weight IM single dose followed by Oxytetracycline @ 10 mg/kg body weight IV in 500 ml of NS for 5 days and Prednisolone @ 0.25 mg/kg body weight IM for 3 days along with supportive therapy. The cattle well responded to the therapy and complete regression of ocular signs was observed within one week of treatment.
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| first_indexed | 2024-03-11T22:06:12Z |
| format | Article |
| id | doaj.art-bc094d1699d046a9928eafc24646f0fc |
| institution | Directory Open Access Journal |
| issn | 1735-7020 2008-238X |
| language | English |
| last_indexed | 2024-03-11T22:06:12Z |
| publishDate | 2023-09-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Parasitology |
| spelling | doaj.art-bc094d1699d046a9928eafc24646f0fc2023-09-25T05:54:28ZengTehran University of Medical SciencesIranian Journal of Parasitology1735-70202008-238X2023-09-01183Theileria annulata Induced Bilateral Ocular Signs in Cattle and its Successful Therapeutic Management: A Case ReportAnil Kumar0Pankaj Kumar1Sonam Bhatt2Ajeet Kumar3G.D Singh4Ankesh Kumar5Department of Veterinary Medicine, Bihar Veterinary College, BASU, Patna, Bihar, IndiaDepartment of Veterinary Parasitology, Bihar Veterinary College, BASU, Patna, Bihar, IndiaDepartment of Veterinary Medicine, Bihar Veterinary College, BASU, Patna, Bihar, IndiaDepartment of Veterinary Biochemistry, Bihar Veterinary College, BASU, Patna, Bihar, IndiaDepartment of VCC, Bihar Veterinary College, BASU, Patna, Bihar, IndiaDepartment of VCC, Bihar Veterinary College, BASU, Patna, Bihar, India Bovine tropical theileriosis is one of the potentially fatal disease of dairy cattle, which is caused by hemoparasite Theleria annulata. About seven years old cross-bred cow was presented with complaint of pyrexia, inappetance, lacrimation and ocular swelling since last 5 days. The clinical examination showed elevated rectal temperature (39.4 0C), mild enlarged pre-scapular lymph nodes, bilateral bulging of temporal fossa, protruded pale and icteric conjunctivae of the eyes with lacrimation and presence of ticks on body. The case was suspected for haemoprotozoan disease. Blood and serum sample were collected for hematological, blood smear examination and molecular examination (PCR), and biochemical analysis respectively. Microscopic examination of blood smear revealed intra-erythrocytic signet ring shaped periplasm of Theileria annulata. Hemato-biochemical examination revealed anemia, hypoproteinemia, hypoalbuminemia and jaundice. Further, PCR assay was done using T. annulata-specific primer pair, Cyto b1 gene targeting the amplicon of 312 bp showed specific band on Gel-electrophoresis. Therapeutic regimen was started with Buparvaquone @ 2.5 mg/kg body weight IM single dose followed by Oxytetracycline @ 10 mg/kg body weight IV in 500 ml of NS for 5 days and Prednisolone @ 0.25 mg/kg body weight IM for 3 days along with supportive therapy. The cattle well responded to the therapy and complete regression of ocular signs was observed within one week of treatment. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/3843Ocular signsTheleria annulataBuparvaquone |
| spellingShingle | Anil Kumar Pankaj Kumar Sonam Bhatt Ajeet Kumar G.D Singh Ankesh Kumar Theileria annulata Induced Bilateral Ocular Signs in Cattle and its Successful Therapeutic Management: A Case Report Iranian Journal of Parasitology Ocular signs Theleria annulata Buparvaquone |
| title | Theileria annulata Induced Bilateral Ocular Signs in Cattle and its Successful Therapeutic Management: A Case Report |
| title_full | Theileria annulata Induced Bilateral Ocular Signs in Cattle and its Successful Therapeutic Management: A Case Report |
| title_fullStr | Theileria annulata Induced Bilateral Ocular Signs in Cattle and its Successful Therapeutic Management: A Case Report |
| title_full_unstemmed | Theileria annulata Induced Bilateral Ocular Signs in Cattle and its Successful Therapeutic Management: A Case Report |
| title_short | Theileria annulata Induced Bilateral Ocular Signs in Cattle and its Successful Therapeutic Management: A Case Report |
| title_sort | theileria annulata induced bilateral ocular signs in cattle and its successful therapeutic management a case report |
| topic | Ocular signs Theleria annulata Buparvaquone |
| url | https://ijpa.tums.ac.ir/index.php/ijpa/article/view/3843 |
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