Restoration of brain dystrophin using tricyclo-DNA ASOs restores neurobehavioral deficits in DMD mice
Main Authors: | Muthukumar Karuppasamy, Matthew S. Alexander |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
|
Series: | Molecular Therapy: Nucleic Acids |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2162253123000938 |
Similar Items
-
Partial restoration of brain dystrophin by tricyclo-DNA antisense oligonucleotides alleviates emotional deficits in mdx52 mice
by: Amel Saoudi, et al.
Published: (2023-06-01) -
Link between MHC Fiber Type and Restoration of Dystrophin Expression and Key Components of the DAPC by Tricyclo-DNA-Mediated Exon Skipping
by: Saleh Omairi, et al.
Published: (2017-12-01) -
Targeted genome editing in vivo corrects a Dmd duplication restoring wild‐type dystrophin expression
by: Eleonora Maino, et al.
Published: (2021-05-01) -
Tricyclo-DNA: A promising chemistry for the synthesis of antisense molecules for splice-switching approaches in DMD
by: Goyenvalle, A, et al.
Published: (2012) -
Full-Length Dystrophin Restoration via Targeted Exon Addition in DMD-Patient Specific iPSCs and Cardiomyocytes
by: Rou Xiao, et al.
Published: (2022-08-01)