Clinicopathologic Correlation of White, Non scrapable Oral Mucosal Surface Lesions: A Study of 100 Cases

Introduction: White, non scrapable lesions are commonly seen in the oral cavity. Based on their history and clinical appearance, most of these lesions can be easily diagnosed, but sometimes diagnosis may go wrong. In order to arrive to a confirmative diagnosis, histopathological assessment is ne...

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Main Authors: Mohammed Abidullah, Vandana Raghunath, Tanveer Karpe, Syed Akifuddin, Shahid Imran, Venkata Naga Nalini Dhurjati, Mohammed Ahtesham Aleem, Farheen Khatoon
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-02-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/7226/16950_CE[Ra]_F(Sh)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf
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author Mohammed Abidullah
Vandana Raghunath
Tanveer Karpe
Syed Akifuddin
Shahid Imran
Venkata Naga Nalini Dhurjati
Mohammed Ahtesham Aleem
Farheen Khatoon
author_facet Mohammed Abidullah
Vandana Raghunath
Tanveer Karpe
Syed Akifuddin
Shahid Imran
Venkata Naga Nalini Dhurjati
Mohammed Ahtesham Aleem
Farheen Khatoon
author_sort Mohammed Abidullah
collection DOAJ
description Introduction: White, non scrapable lesions are commonly seen in the oral cavity. Based on their history and clinical appearance, most of these lesions can be easily diagnosed, but sometimes diagnosis may go wrong. In order to arrive to a confirmative diagnosis, histopathological assessment is needed in many cases, if not all. Aims: 1) To find out the prevalence of clinically diagnosed oral white, non scrapable lesions. 2) To find out the prevalence of histopathologically diagnosed oral white, non scrapable lesions. 3) To correlate the clinical and histopathological diagnosis in the above lesions. Materials and Methods: A total of 100 cases of oral white, non scrapable lesions were included in the study. Based on their history and clinical presentation, clinical provisional diagnosis was made. Then biopsy was done and confirmatory histopathological diagnosis was given and both were correlated. In order to correlate clinical and histopathological diagnosis Discrepancy Index (DI) was calculated for all the cases. Results: Based on clinical diagnosis, there were 59 cases (59%) of leukoplakia, 29 cases (29%) of lichen planus and six cases (6%) of lichenoid reaction; whereas, based on histopathological diagnosis, there were 66 cases (66%) of leukoplakia epithelial hyperplasia and hyperkeratosis (leukoplakia) and 30 cases (30%) of lichen planus. Seventy eight clinically diagnosed cases (78%) correlated with the histopathological diagnosis and 22 cases (22%) did not correlate. The total discrepancy index was 22%. Conclusion: A clinician needs to be aware of oral white, non scrapable lesions. Due to the overlapping of many clinical features in some of these lesions and also due to their malignant potential, a histopathological confirmative diagnosis is recommended.
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spelling doaj.art-bc1043595fac48c1a48f9701a9cfb39b2022-12-21T23:18:51ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-02-01102ZC38ZC4110.7860/JCDR/2016/16950.7226Clinicopathologic Correlation of White, Non scrapable Oral Mucosal Surface Lesions: A Study of 100 CasesMohammed Abidullah0Vandana Raghunath1Tanveer Karpe2Syed Akifuddin3Shahid Imran4Venkata Naga Nalini Dhurjati5Mohammed Ahtesham Aleem6Farheen Khatoon7Assistant Professor, Department of Oral & Maxillofacial Pathology, S.B Patil Dental College and Hospital, Bidar, Karnataka, India. Professor and HOD, Department of Oral & Maxillofacial Pathology, Narayana Dental College & Hospital, Nellore, AP, India.Professor, Department of Oral & Maxillofacial Surgery, S.B Patil Dental College and Hospital, Bidar, Karnataka, India.Reader, Department of Oral & Maxillofacial Surgery, Daswani Dental College & Hospital, Kota, Rajasthan, India.Post Graduate Student, Department of Oral Medicine & Radiology, MNR Dental College, Sanga Reddy, Telagana, India.Graduate Student, Ragas Dental College, Chennai, Tamil Nadu, India.Consulting Oral & Maxillofacial Surgeon, Life Prime Dental Hospital, Hyderabad, Telangana, India.Director, Dentomax Dental & Maxillofacial Solutions, Hyderabad, Telangana, India.Introduction: White, non scrapable lesions are commonly seen in the oral cavity. Based on their history and clinical appearance, most of these lesions can be easily diagnosed, but sometimes diagnosis may go wrong. In order to arrive to a confirmative diagnosis, histopathological assessment is needed in many cases, if not all. Aims: 1) To find out the prevalence of clinically diagnosed oral white, non scrapable lesions. 2) To find out the prevalence of histopathologically diagnosed oral white, non scrapable lesions. 3) To correlate the clinical and histopathological diagnosis in the above lesions. Materials and Methods: A total of 100 cases of oral white, non scrapable lesions were included in the study. Based on their history and clinical presentation, clinical provisional diagnosis was made. Then biopsy was done and confirmatory histopathological diagnosis was given and both were correlated. In order to correlate clinical and histopathological diagnosis Discrepancy Index (DI) was calculated for all the cases. Results: Based on clinical diagnosis, there were 59 cases (59%) of leukoplakia, 29 cases (29%) of lichen planus and six cases (6%) of lichenoid reaction; whereas, based on histopathological diagnosis, there were 66 cases (66%) of leukoplakia epithelial hyperplasia and hyperkeratosis (leukoplakia) and 30 cases (30%) of lichen planus. Seventy eight clinically diagnosed cases (78%) correlated with the histopathological diagnosis and 22 cases (22%) did not correlate. The total discrepancy index was 22%. Conclusion: A clinician needs to be aware of oral white, non scrapable lesions. Due to the overlapping of many clinical features in some of these lesions and also due to their malignant potential, a histopathological confirmative diagnosis is recommended.https://jcdr.net/articles/PDF/7226/16950_CE[Ra]_F(Sh)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdffrictional keratosisleukoedemaleukoplakialichenoid reactionlichen planus
spellingShingle Mohammed Abidullah
Vandana Raghunath
Tanveer Karpe
Syed Akifuddin
Shahid Imran
Venkata Naga Nalini Dhurjati
Mohammed Ahtesham Aleem
Farheen Khatoon
Clinicopathologic Correlation of White, Non scrapable Oral Mucosal Surface Lesions: A Study of 100 Cases
Journal of Clinical and Diagnostic Research
frictional keratosis
leukoedema
leukoplakia
lichenoid reaction
lichen planus
title Clinicopathologic Correlation of White, Non scrapable Oral Mucosal Surface Lesions: A Study of 100 Cases
title_full Clinicopathologic Correlation of White, Non scrapable Oral Mucosal Surface Lesions: A Study of 100 Cases
title_fullStr Clinicopathologic Correlation of White, Non scrapable Oral Mucosal Surface Lesions: A Study of 100 Cases
title_full_unstemmed Clinicopathologic Correlation of White, Non scrapable Oral Mucosal Surface Lesions: A Study of 100 Cases
title_short Clinicopathologic Correlation of White, Non scrapable Oral Mucosal Surface Lesions: A Study of 100 Cases
title_sort clinicopathologic correlation of white non scrapable oral mucosal surface lesions a study of 100 cases
topic frictional keratosis
leukoedema
leukoplakia
lichenoid reaction
lichen planus
url https://jcdr.net/articles/PDF/7226/16950_CE[Ra]_F(Sh)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf
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