Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation
The exopolysaccharide galactosaminogalactan (GAG) is an important virulence factor of the fungal pathogen Aspergillus fumigatus. Here, the authors study an A. fumigatus enzyme that deacetylates GAG in a metal-dependent manner and constitutes a founding member of a new carbohydrate esterase family.
Bibliographic Details
| Main Authors: |
Natalie C. Bamford,
François Le Mauff,
Jaime C. Van Loon,
Hanna Ostapska,
Brendan D. Snarr,
Yongzhen Zhang,
Elena N. Kitova,
John S. Klassen,
Jeroen D. C. Codée,
Donald C. Sheppard,
P. Lynne Howell |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2020-05-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-16144-5
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