Different Body Fluid Biopsies for Detecting Minimal Residual Disease in Lung Cancer: a Review of the Latest Advances
Post-treatment recurrence is a major difficulty in the treatment of lung cancer, one of the deadliest cancers worldwide. Minimal residual disease (MRD) as a "bridgehead" for the recurrence of solid tumors, is described as the presence of free circulating tumor cells or other tumor...
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| Format: | Article |
| Language: | zho |
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Chinese General Practice Publishing House Co., Ltd
2023-01-01
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| Series: | Zhongguo quanke yixue |
| Subjects: | |
| Online Access: | https://www.chinagp.net/fileup/1007-9572/PDF/zx20220641.pdf |
| _version_ | 1797216857076269056 |
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| author | YAN Xing, LIU Shanmei, LIU Changhong |
| author_facet | YAN Xing, LIU Shanmei, LIU Changhong |
| author_sort | YAN Xing, LIU Shanmei, LIU Changhong |
| collection | DOAJ |
| description | Post-treatment recurrence is a major difficulty in the treatment of lung cancer, one of the deadliest cancers worldwide. Minimal residual disease (MRD) as a "bridgehead" for the recurrence of solid tumors, is described as the presence of free circulating tumor cells or other tumor cell derivatives in the biological fluid of patients without any clinical cancer symptoms after the primary tumor treatment. China recently issued its first Consensus on the Detection and Clinical Application of MRD in Lung Cancer, aiming at improving the postoperative individualized treatment for lung cancer patients in accordance with the MRD status detected by the liquid biopsy. We reviewed the latest advances in the use of several most widely used body fluids (peripheral blood, urine, saliva, sputum and pleural effusion) in the detection of MRD in lung cancer, and discussed their values in guiding the precise treatment of MRD in lung cancer. |
| first_indexed | 2024-04-24T11:52:37Z |
| format | Article |
| id | doaj.art-bc13d9d4a8e74533b74a4ec77fae4c74 |
| institution | Directory Open Access Journal |
| issn | 1007-9572 |
| language | zho |
| last_indexed | 2024-04-24T11:52:37Z |
| publishDate | 2023-01-01 |
| publisher | Chinese General Practice Publishing House Co., Ltd |
| record_format | Article |
| series | Zhongguo quanke yixue |
| spelling | doaj.art-bc13d9d4a8e74533b74a4ec77fae4c742024-04-09T07:01:23ZzhoChinese General Practice Publishing House Co., LtdZhongguo quanke yixue1007-95722023-01-01260328028610.12114/j.issn.1007-9572.2022.0641Different Body Fluid Biopsies for Detecting Minimal Residual Disease in Lung Cancer: a Review of the Latest AdvancesYAN Xing, LIU Shanmei, LIU Changhong01.Department of Thoracic Surgery, the Second Hospital of Dalian Medical University, Dalian 116000, China;2.Inner Mongolia Medical University, Hohhot 015000, ChinaPost-treatment recurrence is a major difficulty in the treatment of lung cancer, one of the deadliest cancers worldwide. Minimal residual disease (MRD) as a "bridgehead" for the recurrence of solid tumors, is described as the presence of free circulating tumor cells or other tumor cell derivatives in the biological fluid of patients without any clinical cancer symptoms after the primary tumor treatment. China recently issued its first Consensus on the Detection and Clinical Application of MRD in Lung Cancer, aiming at improving the postoperative individualized treatment for lung cancer patients in accordance with the MRD status detected by the liquid biopsy. We reviewed the latest advances in the use of several most widely used body fluids (peripheral blood, urine, saliva, sputum and pleural effusion) in the detection of MRD in lung cancer, and discussed their values in guiding the precise treatment of MRD in lung cancer.https://www.chinagp.net/fileup/1007-9572/PDF/zx20220641.pdflung neoplasms|liquid biopsy|neoplasm, residual|circulating tumor dna|review |
| spellingShingle | YAN Xing, LIU Shanmei, LIU Changhong Different Body Fluid Biopsies for Detecting Minimal Residual Disease in Lung Cancer: a Review of the Latest Advances Zhongguo quanke yixue lung neoplasms|liquid biopsy|neoplasm, residual|circulating tumor dna|review |
| title | Different Body Fluid Biopsies for Detecting Minimal Residual Disease in Lung Cancer: a Review of the Latest Advances |
| title_full | Different Body Fluid Biopsies for Detecting Minimal Residual Disease in Lung Cancer: a Review of the Latest Advances |
| title_fullStr | Different Body Fluid Biopsies for Detecting Minimal Residual Disease in Lung Cancer: a Review of the Latest Advances |
| title_full_unstemmed | Different Body Fluid Biopsies for Detecting Minimal Residual Disease in Lung Cancer: a Review of the Latest Advances |
| title_short | Different Body Fluid Biopsies for Detecting Minimal Residual Disease in Lung Cancer: a Review of the Latest Advances |
| title_sort | different body fluid biopsies for detecting minimal residual disease in lung cancer a review of the latest advances |
| topic | lung neoplasms|liquid biopsy|neoplasm, residual|circulating tumor dna|review |
| url | https://www.chinagp.net/fileup/1007-9572/PDF/zx20220641.pdf |
| work_keys_str_mv | AT yanxingliushanmeiliuchanghong differentbodyfluidbiopsiesfordetectingminimalresidualdiseaseinlungcancerareviewofthelatestadvances |