The Ethanolic Extract of Caesalpinia sappan Heartwood Inhibits Cerebral Ischemia/Reperfusion Injury in a Rat Model Through a Multi-Targeted Pharmacological Mechanism

The Ethanolic Extract of Caesalpinia sappan Heartwood Inhibits Cerebral Ischemia/Reperfusion Injury in a Rat Model Through a Multi-Targeted Pharmacological Mechanism

Background:Caesalpinia sappan L. (C. sappan) is a traditional Chinese medicinal plant. The dried heartwood of C. sappan (also known as Sappan wood) has been widely used for the folkloric medical treatment of ischemic cerebral stroke in China. However, the detailed underlying pharmacological mechanis...

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Bibliographic Details
Main Authors:	Yan-Jun Wan, Li Xu, Wen-Ting Song, Yu-Qi Liu, Li-Chao Wang, Ming-Bo Zhao, Yong Jiang, Lian-Ying Liu, Ke-Wu Zeng, Peng-Fei Tu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-02-01
Series:	Frontiers in Pharmacology
Subjects:	Caesalpinia sappan L. middle cerebral artery occlusion oxygen-glucose deprivation/reperfusion neuroprotection multi-target mechanism
Online Access:	https://www.frontiersin.org/article/10.3389/fphar.2019.00029/full

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