Antitumorigenic Effect of Tramadol and Synergistic Effect With Doxorubicin in Human Breast Cancer Cells

Antitumorigenic Effect of Tramadol and Synergistic Effect With Doxorubicin in Human Breast Cancer Cells

BackgroundBreast cancer in women is one of the leading causes of cancer mortality worldwide, and curative therapy is the main focus of clinical treatment. Anesthetic-analgesic techniques might alter stress responses and immunity and thereby influence outcomes in cancer patients. This study investiga...

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Bibliographic Details
Main Authors: Yi-Hsuan Huang, Sung-How Sue, Zih-Syuan Wu, Shih-Ming Huang, Shih-Yu Lee, Zhi-Fu Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
breast cancer
doxorubicin
epithelial–mesenchymal transition
HIF-1α
tramadol
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.811716/full

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