Topical Oral Medicaments in Traditional Persian Medicine

Objectives: Traditional, topically used oral medicaments are of great importance in the treatment of both oral and systemic diseases. Therefore, the aim of this study was to review the indications of various drug delivery forms and active ingredients of currently used medications in complementary me...

Full description

Bibliographic Details
Main Authors: Zoleikha Khoshbakht, Mohammadali Torbati, Laleh Khodaie, Ehsan Khashabi
Format: Article
Language:English
Published: Aras Part Medical International Press 2020-01-01
Series:Crescent Journal of Medical and Biological Sciences
Subjects:
Online Access:http://www.cjmb.org/pdf.php?id=322
_version_ 1817991004383346688
author Zoleikha Khoshbakht
Mohammadali Torbati
Laleh Khodaie
Ehsan Khashabi
author_facet Zoleikha Khoshbakht
Mohammadali Torbati
Laleh Khodaie
Ehsan Khashabi
author_sort Zoleikha Khoshbakht
collection DOAJ
description Objectives: Traditional, topically used oral medicaments are of great importance in the treatment of both oral and systemic diseases. Therefore, the aim of this study was to review the indications of various drug delivery forms and active ingredients of currently used medications in complementary medicine, as well as the results of recent research to find any possible conformity between their traditional and recent pharmaceutical properties. Methods: In this review article, different resources including electronica databases, hand searching, the screening of reference lists and contacting experts were extensively performed, followed by categorizing the extracted data. Results: Based on the results, 6 drug forms were found in gaseous, liquid, and solid states with more than 70 formulations. Liquid and gaseous forms were mainly used to manage systemic conditions and solid forms were mainly applied for local treatments. In addition, the investigation of about 50 herbal components showed that the traditional therapeutic effects of the vast majority of the ingredients were in line with those of the recent studies. However, no clinical studies were found regarding the traditionally mentioned systemic effects after the topical use of this medicament in the form of gargles or mouthrinse. Conclusions: In general, the side effects of oral and injectable drugs, as well as the specific advantages of oral mucosa in achieving the topical and systemic effects and the variety of the plant components of Iranian traditional oral medicament might have high potentials for finding new drugs and improving treatment strategies of some systemic diseases such as central nervous system diseases and depression.
first_indexed 2024-04-14T01:07:36Z
format Article
id doaj.art-bc1faa8a14aa47a0b70c1d4680a1b948
institution Directory Open Access Journal
issn 2148-9696
language English
last_indexed 2024-04-14T01:07:36Z
publishDate 2020-01-01
publisher Aras Part Medical International Press
record_format Article
series Crescent Journal of Medical and Biological Sciences
spelling doaj.art-bc1faa8a14aa47a0b70c1d4680a1b9482022-12-22T02:21:11ZengAras Part Medical International PressCrescent Journal of Medical and Biological Sciences2148-96962020-01-01711721cjmb-5026Topical Oral Medicaments in Traditional Persian MedicineZoleikha Khoshbakht0Mohammadali Torbati1Laleh Khodaie2Ehsan Khashabi3Department of Phytopharmacy, Faculty of Traditional Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.Department of Food Science and Technology, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.Medical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.Department of Periodontics, Faculty of Dentistry, Urmia University of Medical Sciences, Urmia, Iran.Objectives: Traditional, topically used oral medicaments are of great importance in the treatment of both oral and systemic diseases. Therefore, the aim of this study was to review the indications of various drug delivery forms and active ingredients of currently used medications in complementary medicine, as well as the results of recent research to find any possible conformity between their traditional and recent pharmaceutical properties. Methods: In this review article, different resources including electronica databases, hand searching, the screening of reference lists and contacting experts were extensively performed, followed by categorizing the extracted data. Results: Based on the results, 6 drug forms were found in gaseous, liquid, and solid states with more than 70 formulations. Liquid and gaseous forms were mainly used to manage systemic conditions and solid forms were mainly applied for local treatments. In addition, the investigation of about 50 herbal components showed that the traditional therapeutic effects of the vast majority of the ingredients were in line with those of the recent studies. However, no clinical studies were found regarding the traditionally mentioned systemic effects after the topical use of this medicament in the form of gargles or mouthrinse. Conclusions: In general, the side effects of oral and injectable drugs, as well as the specific advantages of oral mucosa in achieving the topical and systemic effects and the variety of the plant components of Iranian traditional oral medicament might have high potentials for finding new drugs and improving treatment strategies of some systemic diseases such as central nervous system diseases and depression.http://www.cjmb.org/pdf.php?id=322ethno-medicineethno-pharmacologytraditional persian medicineoralmedicaments
spellingShingle Zoleikha Khoshbakht
Mohammadali Torbati
Laleh Khodaie
Ehsan Khashabi
Topical Oral Medicaments in Traditional Persian Medicine
Crescent Journal of Medical and Biological Sciences
ethno-medicine
ethno-pharmacology
traditional persian medicine
oral
medicaments
title Topical Oral Medicaments in Traditional Persian Medicine
title_full Topical Oral Medicaments in Traditional Persian Medicine
title_fullStr Topical Oral Medicaments in Traditional Persian Medicine
title_full_unstemmed Topical Oral Medicaments in Traditional Persian Medicine
title_short Topical Oral Medicaments in Traditional Persian Medicine
title_sort topical oral medicaments in traditional persian medicine
topic ethno-medicine
ethno-pharmacology
traditional persian medicine
oral
medicaments
url http://www.cjmb.org/pdf.php?id=322
work_keys_str_mv AT zoleikhakhoshbakht topicaloralmedicamentsintraditionalpersianmedicine
AT mohammadalitorbati topicaloralmedicamentsintraditionalpersianmedicine
AT lalehkhodaie topicaloralmedicamentsintraditionalpersianmedicine
AT ehsankhashabi topicaloralmedicamentsintraditionalpersianmedicine