Diagnosis of Ischemic Stroke: As Simple as Possible

The absolute majority of strokes in high-income countries, roughly 91%, are of ischemic origin. This review is focused on acute ischemic stroke (AIS) with large vessel occlusion (LVO) in the anterior circulation, which is considered the most devastating subtype of AIS. Moreover, stroke survivors imp...

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Main Authors: Hana Malikova, Jiri Weichet
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/12/6/1452
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author Hana Malikova
Jiri Weichet
author_facet Hana Malikova
Jiri Weichet
author_sort Hana Malikova
collection DOAJ
description The absolute majority of strokes in high-income countries, roughly 91%, are of ischemic origin. This review is focused on acute ischemic stroke (AIS) with large vessel occlusion (LVO) in the anterior circulation, which is considered the most devastating subtype of AIS. Moreover, stroke survivors impose substantial direct and indirect costs of care as well as costs due to productivity loss. We review of diagnostic possibilities of individual imaging methods such as computed tomography and magnetic resonance imaging, and discuss their pros and cons in the imaging of AIS. The goals of non-invasive imaging in AIS are as follows: (a) to rule out intracranial hemorrhage and to quickly exclude hemorrhagic stroke and contraindications for intravenous thrombolysis; (b) to identify potential LVO and its localization and to quickly provide guidance for endovascular treatment; (c) to assess/estimate the volume or size of the ischemic core. We suggest fast diagnostic management, which is able to quickly satisfy the above-mentioned diagnostic goals in AIS with LVO.
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spelling doaj.art-bc1fde538abb45609487e47082340d542023-11-23T16:18:24ZengMDPI AGDiagnostics2075-44182022-06-01126145210.3390/diagnostics12061452Diagnosis of Ischemic Stroke: As Simple as PossibleHana Malikova0Jiri Weichet1Department of Radiology, Third Faculty of Medicine, Faculty Hospital Kralovske Vinohrady, Charles University, Srobarova 1150/50, 11000 Prague, Czech RepublicDepartment of Radiology, Third Faculty of Medicine, Faculty Hospital Kralovske Vinohrady, Charles University, Srobarova 1150/50, 11000 Prague, Czech RepublicThe absolute majority of strokes in high-income countries, roughly 91%, are of ischemic origin. This review is focused on acute ischemic stroke (AIS) with large vessel occlusion (LVO) in the anterior circulation, which is considered the most devastating subtype of AIS. Moreover, stroke survivors impose substantial direct and indirect costs of care as well as costs due to productivity loss. We review of diagnostic possibilities of individual imaging methods such as computed tomography and magnetic resonance imaging, and discuss their pros and cons in the imaging of AIS. The goals of non-invasive imaging in AIS are as follows: (a) to rule out intracranial hemorrhage and to quickly exclude hemorrhagic stroke and contraindications for intravenous thrombolysis; (b) to identify potential LVO and its localization and to quickly provide guidance for endovascular treatment; (c) to assess/estimate the volume or size of the ischemic core. We suggest fast diagnostic management, which is able to quickly satisfy the above-mentioned diagnostic goals in AIS with LVO.https://www.mdpi.com/2075-4418/12/6/1452MRICTlarge vessel occlusionthrombectomy
spellingShingle Hana Malikova
Jiri Weichet
Diagnosis of Ischemic Stroke: As Simple as Possible
Diagnostics
MRI
CT
large vessel occlusion
thrombectomy
title Diagnosis of Ischemic Stroke: As Simple as Possible
title_full Diagnosis of Ischemic Stroke: As Simple as Possible
title_fullStr Diagnosis of Ischemic Stroke: As Simple as Possible
title_full_unstemmed Diagnosis of Ischemic Stroke: As Simple as Possible
title_short Diagnosis of Ischemic Stroke: As Simple as Possible
title_sort diagnosis of ischemic stroke as simple as possible
topic MRI
CT
large vessel occlusion
thrombectomy
url https://www.mdpi.com/2075-4418/12/6/1452
work_keys_str_mv AT hanamalikova diagnosisofischemicstrokeassimpleaspossible
AT jiriweichet diagnosisofischemicstrokeassimpleaspossible