Carcinomas in the bladder with papillary and pseudopapillary morphology - not always urothelial
Abstract Background Urothelial carcinoma shows wide plasticity and broad morphologic spectrum. In many instances, the presence of papillary morphology is reassuring of the urothelial histogenesis of a high-grade invasive lesion but is not pathognomonic. Case presentation We reported herein four case...
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| Format: | Article |
| Language: | English |
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BMC
2020-11-01
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| Series: | Surgical and Experimental Pathology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s42047-020-00078-9 |
| _version_ | 1828787294176280576 |
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| author | Daniel Abensur Athanazio Maiara Ferreira de Souza Maria Estela Pompeu do Amaral |
| author_facet | Daniel Abensur Athanazio Maiara Ferreira de Souza Maria Estela Pompeu do Amaral |
| author_sort | Daniel Abensur Athanazio |
| collection | DOAJ |
| description | Abstract Background Urothelial carcinoma shows wide plasticity and broad morphologic spectrum. In many instances, the presence of papillary morphology is reassuring of the urothelial histogenesis of a high-grade invasive lesion but is not pathognomonic. Case presentation We reported herein four cases of carcinomas in the bladder with papillary morphology that had a final diagnosis different from urothelial carcinoma (3% of cases in a 42-month period). In high-grade tumors involving the urinary tract, the presence of papillary/pseudopapillary morphology is not sufficient to render a diagnosis of papillary urothelial carcinoma. Prostate adenocarcinoma, primary bladder adenocarcinoma or metastasis must be excluded in selected case scenarios. |
| first_indexed | 2024-12-12T00:28:45Z |
| format | Article |
| id | doaj.art-bc1ff95fbbbd49c9aed4afcbf70212d9 |
| institution | Directory Open Access Journal |
| issn | 2520-8454 |
| language | English |
| last_indexed | 2024-12-12T00:28:45Z |
| publishDate | 2020-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Surgical and Experimental Pathology |
| spelling | doaj.art-bc1ff95fbbbd49c9aed4afcbf70212d92022-12-22T00:44:33ZengBMCSurgical and Experimental Pathology2520-84542020-11-01311510.1186/s42047-020-00078-9Carcinomas in the bladder with papillary and pseudopapillary morphology - not always urothelialDaniel Abensur Athanazio0Maiara Ferreira de Souza1Maria Estela Pompeu do Amaral2Hospital Universitário Professor Edgard SantosImagepat Laboratory, Rua Lucaia, 209 - Edf. EventusEmpresarialImagepat Laboratory, Rua Lucaia, 209 - Edf. EventusEmpresarialAbstract Background Urothelial carcinoma shows wide plasticity and broad morphologic spectrum. In many instances, the presence of papillary morphology is reassuring of the urothelial histogenesis of a high-grade invasive lesion but is not pathognomonic. Case presentation We reported herein four cases of carcinomas in the bladder with papillary morphology that had a final diagnosis different from urothelial carcinoma (3% of cases in a 42-month period). In high-grade tumors involving the urinary tract, the presence of papillary/pseudopapillary morphology is not sufficient to render a diagnosis of papillary urothelial carcinoma. Prostate adenocarcinoma, primary bladder adenocarcinoma or metastasis must be excluded in selected case scenarios.http://link.springer.com/article/10.1186/s42047-020-00078-9Urologic neoplasmsBladder cancerPathology |
| spellingShingle | Daniel Abensur Athanazio Maiara Ferreira de Souza Maria Estela Pompeu do Amaral Carcinomas in the bladder with papillary and pseudopapillary morphology - not always urothelial Surgical and Experimental Pathology Urologic neoplasms Bladder cancer Pathology |
| title | Carcinomas in the bladder with papillary and pseudopapillary morphology - not always urothelial |
| title_full | Carcinomas in the bladder with papillary and pseudopapillary morphology - not always urothelial |
| title_fullStr | Carcinomas in the bladder with papillary and pseudopapillary morphology - not always urothelial |
| title_full_unstemmed | Carcinomas in the bladder with papillary and pseudopapillary morphology - not always urothelial |
| title_short | Carcinomas in the bladder with papillary and pseudopapillary morphology - not always urothelial |
| title_sort | carcinomas in the bladder with papillary and pseudopapillary morphology not always urothelial |
| topic | Urologic neoplasms Bladder cancer Pathology |
| url | http://link.springer.com/article/10.1186/s42047-020-00078-9 |
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