A Systematic Review on Drugs Acting as Nicotinic Acetylcholine Receptor Agonists in the Treatment of Dementia

A Systematic Review on Drugs Acting as Nicotinic Acetylcholine Receptor Agonists in the Treatment of Dementia

Acetylcholine signaling is attenuated in early Alzheimer’s disease (AD) and other dementias. A significant reduction in the expression of nicotinic acetylcholine receptors (nAChRs) in the brain of AD patients has also been reported in several molecular biological and in situ labeling studies. The mo...

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Bibliographic Details
Main Authors: Alessio Crestini, Elena Carbone, Roberto Rivabene, Antonio Ancidoni, Paolo Rosa, Ada Maria Tata, Elisa Fabrizi, Nicoletta Locuratolo, Nicola Vanacore, Eleonora Lacorte, Paola Piscopo
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cells
Subjects:
nicotinic acetylcholine receptor
nicotinic agonists
dementia
Alzheimer’s disease
neurodegenerative disease
disease-modifying therapies
Online Access:https://www.mdpi.com/2073-4409/13/3/237

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