Construction of Biocompatible Hydrogel Scaffolds With a Long-Term Drug Release for Facilitating Cartilage Repair

Construction of Biocompatible Hydrogel Scaffolds With a Long-Term Drug Release for Facilitating Cartilage Repair

In tissue engineering, hydrogel scaffolds allow various cells to be cultured and grown in vitro and then implanted to repair or replace the damaged areas. Here in this work, kartogenin (KGN), an effectively chondro-inductive non-protein bioactive drug molecule, was incorporated into a composite hydr...

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Bibliographic Details
Main Authors: Wei Zhang, Rui Chen, Xiong Xu, Liang Zhu, Yanbin Liu, XiaoJie Yu, GuoKe Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
BMSCs
cartilage regeneration
hydrogel scaffold
KGN
long-term release
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.922032/full

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