Influenza A and influenza B antibody determination in an Austrian cohort

Influenza is an infectious respiratory disease caused by influenza A and B, which is a virus characterized by a high mutation rate with new strains appearing regularly, making regular booster vaccinations necessary.In this study, we evaluated the immune status of Influenza A and B by using ELISA. A...

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Main Authors: Elisabeth Mara, Johannes Gratzer, Tobias Mader, Thomas Pekar
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Clinical Immunology Communications
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772613422000221
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author Elisabeth Mara
Johannes Gratzer
Tobias Mader
Thomas Pekar
author_facet Elisabeth Mara
Johannes Gratzer
Tobias Mader
Thomas Pekar
author_sort Elisabeth Mara
collection DOAJ
description Influenza is an infectious respiratory disease caused by influenza A and B, which is a virus characterized by a high mutation rate with new strains appearing regularly, making regular booster vaccinations necessary.In this study, we evaluated the immune status of Influenza A and B by using ELISA. A questionnaire was utilized to appraise the immunization anamnesis and the stance on vaccination.In total, 202 probands participated in this study. 35.6% of the probands were vaccinated, 10.9% indicated a confirmed influenza infection. 88.1% had a positive influenza A titer, whereas a positive influenza B titer was determined in only 38.6%. Additionally, a correlation between vaccination and titer could be observed.In this study, we were able to show a higher vaccination rate in our cohort than the Austrian average. Additionally, a higher percentage showed a positive influenza A titer compared to influenza B titer.
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spelling doaj.art-bc25dd1974bc41ffbcae9a2a4865ea232022-12-22T02:02:47ZengElsevierClinical Immunology Communications2772-61342022-12-012142144Influenza A and influenza B antibody determination in an Austrian cohortElisabeth Mara0Johannes Gratzer1Tobias Mader2Thomas Pekar3Corresponding author.; University of Applied Science Wiener Neustadt, AustriaUniversity of Applied Science Wiener Neustadt, AustriaUniversity of Applied Science Wiener Neustadt, AustriaUniversity of Applied Science Wiener Neustadt, AustriaInfluenza is an infectious respiratory disease caused by influenza A and B, which is a virus characterized by a high mutation rate with new strains appearing regularly, making regular booster vaccinations necessary.In this study, we evaluated the immune status of Influenza A and B by using ELISA. A questionnaire was utilized to appraise the immunization anamnesis and the stance on vaccination.In total, 202 probands participated in this study. 35.6% of the probands were vaccinated, 10.9% indicated a confirmed influenza infection. 88.1% had a positive influenza A titer, whereas a positive influenza B titer was determined in only 38.6%. Additionally, a correlation between vaccination and titer could be observed.In this study, we were able to show a higher vaccination rate in our cohort than the Austrian average. Additionally, a higher percentage showed a positive influenza A titer compared to influenza B titer.http://www.sciencedirect.com/science/article/pii/S2772613422000221Influenza A and BAntibodyELISA
spellingShingle Elisabeth Mara
Johannes Gratzer
Tobias Mader
Thomas Pekar
Influenza A and influenza B antibody determination in an Austrian cohort
Clinical Immunology Communications
Influenza A and B
Antibody
ELISA
title Influenza A and influenza B antibody determination in an Austrian cohort
title_full Influenza A and influenza B antibody determination in an Austrian cohort
title_fullStr Influenza A and influenza B antibody determination in an Austrian cohort
title_full_unstemmed Influenza A and influenza B antibody determination in an Austrian cohort
title_short Influenza A and influenza B antibody determination in an Austrian cohort
title_sort influenza a and influenza b antibody determination in an austrian cohort
topic Influenza A and B
Antibody
ELISA
url http://www.sciencedirect.com/science/article/pii/S2772613422000221
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AT thomaspekar influenzaaandinfluenzabantibodydeterminationinanaustriancohort