BOLD magnetic resonance imaging in nephrology
Michael E Hall,1,2 Jennifer H Jordan,3 Luis A Juncos,1,2 W Gregory Hundley,3 John E Hall2 1Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA; 2Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA; 3Department of Internal...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2018-03-01
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| Series: | International Journal of Nephrology and Renovascular Disease |
| Subjects: | |
| Online Access: | https://www.dovepress.com/bold-magnetic-resonance-imaging-in-nephrology-peer-reviewed-article-IJNRD |
| _version_ | 1818429287128104960 |
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| author | Hall ME Jordan JH Juncos LA Hundley WG Hall JE |
| author_facet | Hall ME Jordan JH Juncos LA Hundley WG Hall JE |
| author_sort | Hall ME |
| collection | DOAJ |
| description | Michael E Hall,1,2 Jennifer H Jordan,3 Luis A Juncos,1,2 W Gregory Hundley,3 John E Hall2 1Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA; 2Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA; 3Department of Internal Medicine, Section on Cardiovascular Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA Abstract: Magnetic resonance (MR) imaging, a non-invasive modality that provides anatomic and physiologic information, is increasingly used for diagnosis of pathophysiologic conditions and for understanding renal physiology in humans. Although functional MR imaging methods were pioneered to investigate the brain, they also offer powerful techniques for investigation of other organ systems such as the kidneys. However, imaging the kidneys provides unique challenges due to potential complications from contrast agents. Therefore, development of non-contrast techniques to study kidney anatomy and physiology is important. Blood oxygen level-dependent (BOLD) MR is a non-contrast imaging technique that provides functional information related to renal tissue oxygenation in various pathophysiologic conditions. Here we discuss technical considerations, clinical uses and future directions for use of BOLD MR as well as complementary MR techniques to better understand renal pathophysiology. Our intent is to summarize kidney BOLD MR applications for the clinician rather than focusing on the complex physical challenges that functional MR imaging encompasses; however, we briefly discuss some of those issues. Keywords: functional MRI, kidney, oxygenation, chronic kidney disease |
| first_indexed | 2024-12-14T15:15:07Z |
| format | Article |
| id | doaj.art-bc26439f91e34d8abb47a10fbfb617bf |
| institution | Directory Open Access Journal |
| issn | 1178-7058 |
| language | English |
| last_indexed | 2024-12-14T15:15:07Z |
| publishDate | 2018-03-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of Nephrology and Renovascular Disease |
| spelling | doaj.art-bc26439f91e34d8abb47a10fbfb617bf2022-12-21T22:56:23ZengDove Medical PressInternational Journal of Nephrology and Renovascular Disease1178-70582018-03-01Volume 1110311237190BOLD magnetic resonance imaging in nephrologyHall MEJordan JHJuncos LAHundley WGHall JEMichael E Hall,1,2 Jennifer H Jordan,3 Luis A Juncos,1,2 W Gregory Hundley,3 John E Hall2 1Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA; 2Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA; 3Department of Internal Medicine, Section on Cardiovascular Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA Abstract: Magnetic resonance (MR) imaging, a non-invasive modality that provides anatomic and physiologic information, is increasingly used for diagnosis of pathophysiologic conditions and for understanding renal physiology in humans. Although functional MR imaging methods were pioneered to investigate the brain, they also offer powerful techniques for investigation of other organ systems such as the kidneys. However, imaging the kidneys provides unique challenges due to potential complications from contrast agents. Therefore, development of non-contrast techniques to study kidney anatomy and physiology is important. Blood oxygen level-dependent (BOLD) MR is a non-contrast imaging technique that provides functional information related to renal tissue oxygenation in various pathophysiologic conditions. Here we discuss technical considerations, clinical uses and future directions for use of BOLD MR as well as complementary MR techniques to better understand renal pathophysiology. Our intent is to summarize kidney BOLD MR applications for the clinician rather than focusing on the complex physical challenges that functional MR imaging encompasses; however, we briefly discuss some of those issues. Keywords: functional MRI, kidney, oxygenation, chronic kidney disease https://www.dovepress.com/bold-magnetic-resonance-imaging-in-nephrology-peer-reviewed-article-IJNRDFunctional MRIkidneyoxygenation |
| spellingShingle | Hall ME Jordan JH Juncos LA Hundley WG Hall JE BOLD magnetic resonance imaging in nephrology International Journal of Nephrology and Renovascular Disease Functional MRI kidney oxygenation |
| title | BOLD magnetic resonance imaging in nephrology |
| title_full | BOLD magnetic resonance imaging in nephrology |
| title_fullStr | BOLD magnetic resonance imaging in nephrology |
| title_full_unstemmed | BOLD magnetic resonance imaging in nephrology |
| title_short | BOLD magnetic resonance imaging in nephrology |
| title_sort | bold magnetic resonance imaging in nephrology |
| topic | Functional MRI kidney oxygenation |
| url | https://www.dovepress.com/bold-magnetic-resonance-imaging-in-nephrology-peer-reviewed-article-IJNRD |
| work_keys_str_mv | AT hallme boldmagneticresonanceimaginginnephrology AT jordanjh boldmagneticresonanceimaginginnephrology AT juncosla boldmagneticresonanceimaginginnephrology AT hundleywg boldmagneticresonanceimaginginnephrology AT hallje boldmagneticresonanceimaginginnephrology |