A Comparison of the Predictive Role of the Geriatric Nutritional Risk Index and Immunonutritional Parameters for Postoperative Complications in Elderly Patients with Renal Cell Carcinoma
Background The geriatric nutritional risk index (GNRI) is reportedly a useful factor for predicting postoperative complications in elderly patients with several cancers. The aim of this study was to investigate the relationship between postoperative complications and the GNRI in elderly patients wit...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-09-01
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| Series: | Journal of Investigative Surgery |
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| Online Access: | http://dx.doi.org/10.1080/08941939.2020.1762808 |
| _version_ | 1797684628020002816 |
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| author | Daisuke Watanabe Kunihisa Miura Akemi Yamashita Tadaaki Minowa Yuko Uehara Shinobu Mizushima Seiichiro Yoshikawa Akio Mizushima |
| author_facet | Daisuke Watanabe Kunihisa Miura Akemi Yamashita Tadaaki Minowa Yuko Uehara Shinobu Mizushima Seiichiro Yoshikawa Akio Mizushima |
| author_sort | Daisuke Watanabe |
| collection | DOAJ |
| description | Background The geriatric nutritional risk index (GNRI) is reportedly a useful factor for predicting postoperative complications in elderly patients with several cancers. The aim of this study was to investigate the relationship between postoperative complications and the GNRI in elderly patients with renal cell carcinoma (RCC). Materials and Methods The clinical data of 62 patients who were ≥65 years old and underwent open surgery for RCC were analyzed retrospectively. The American Society of Anesthesiologists physical status, Charlson comorbidity index, surgical procedure, body mass index, GNRI, platelet-lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), psoas muscle index (PMI), visceral fat area, and subcutaneous fat area were examined. The association of the GNRI and immunonutritional parameters with postoperative complications was analyzed by the univariate and multivariate analyses. Results Grade ≥ II postoperative complications evaluated by the Clavien-Dindo classification were seen in 11 out of 62 cases. In the Spearman’s correlation test, the GNRI showed a significant negative correlation with the PLR and NLR and a significant positive correlation with the PMI. The group with postoperative complications showed a significantly lower GNRI, higher PLR, and higher NLR than those without complications. In the multivariate analysis, a GNRI ≤92 was independently associated with postoperative complications. Conclusion The GNRI might play an important role in evaluation of the risk of postoperative complications in open surgery for elderly RCC patients. |
| first_indexed | 2024-03-12T00:33:25Z |
| format | Article |
| id | doaj.art-bc2cfb3fa8e6426298c4c5afde273a7a |
| institution | Directory Open Access Journal |
| issn | 0894-1939 1521-0553 |
| language | English |
| last_indexed | 2024-03-12T00:33:25Z |
| publishDate | 2021-09-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Investigative Surgery |
| spelling | doaj.art-bc2cfb3fa8e6426298c4c5afde273a7a2023-09-15T10:07:33ZengTaylor & Francis GroupJournal of Investigative Surgery0894-19391521-05532021-09-0134101072107710.1080/08941939.2020.17628081762808A Comparison of the Predictive Role of the Geriatric Nutritional Risk Index and Immunonutritional Parameters for Postoperative Complications in Elderly Patients with Renal Cell CarcinomaDaisuke Watanabe0Kunihisa Miura1Akemi Yamashita2Tadaaki Minowa3Yuko Uehara4Shinobu Mizushima5Seiichiro Yoshikawa6Akio Mizushima7Department of Palliative Medicine, Juntendo University Graduate School of MedicineDepartment of Anesthesiology and Pain Medicine, Koto HospitalDepartment of Urology, Koto HospitalDepartment of Urology, Koto HospitalDepartment of Palliative Medicine, Juntendo University Graduate School of MedicineDepartment of Anesthesiology and Pain Medicine, Juntendo University School of MedicineCancer Therapeutic Center, Juntendo University Urayasu HospitalDepartment of Palliative Medicine, Juntendo University Graduate School of MedicineBackground The geriatric nutritional risk index (GNRI) is reportedly a useful factor for predicting postoperative complications in elderly patients with several cancers. The aim of this study was to investigate the relationship between postoperative complications and the GNRI in elderly patients with renal cell carcinoma (RCC). Materials and Methods The clinical data of 62 patients who were ≥65 years old and underwent open surgery for RCC were analyzed retrospectively. The American Society of Anesthesiologists physical status, Charlson comorbidity index, surgical procedure, body mass index, GNRI, platelet-lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), psoas muscle index (PMI), visceral fat area, and subcutaneous fat area were examined. The association of the GNRI and immunonutritional parameters with postoperative complications was analyzed by the univariate and multivariate analyses. Results Grade ≥ II postoperative complications evaluated by the Clavien-Dindo classification were seen in 11 out of 62 cases. In the Spearman’s correlation test, the GNRI showed a significant negative correlation with the PLR and NLR and a significant positive correlation with the PMI. The group with postoperative complications showed a significantly lower GNRI, higher PLR, and higher NLR than those without complications. In the multivariate analysis, a GNRI ≤92 was independently associated with postoperative complications. Conclusion The GNRI might play an important role in evaluation of the risk of postoperative complications in open surgery for elderly RCC patients.http://dx.doi.org/10.1080/08941939.2020.1762808geriatric nutritional risk indexplatelet-lymphocyte ratiopostoperative complicationrenal cell carcinoma |
| spellingShingle | Daisuke Watanabe Kunihisa Miura Akemi Yamashita Tadaaki Minowa Yuko Uehara Shinobu Mizushima Seiichiro Yoshikawa Akio Mizushima A Comparison of the Predictive Role of the Geriatric Nutritional Risk Index and Immunonutritional Parameters for Postoperative Complications in Elderly Patients with Renal Cell Carcinoma Journal of Investigative Surgery geriatric nutritional risk index platelet-lymphocyte ratio postoperative complication renal cell carcinoma |
| title | A Comparison of the Predictive Role of the Geriatric Nutritional Risk Index and Immunonutritional Parameters for Postoperative Complications in Elderly Patients with Renal Cell Carcinoma |
| title_full | A Comparison of the Predictive Role of the Geriatric Nutritional Risk Index and Immunonutritional Parameters for Postoperative Complications in Elderly Patients with Renal Cell Carcinoma |
| title_fullStr | A Comparison of the Predictive Role of the Geriatric Nutritional Risk Index and Immunonutritional Parameters for Postoperative Complications in Elderly Patients with Renal Cell Carcinoma |
| title_full_unstemmed | A Comparison of the Predictive Role of the Geriatric Nutritional Risk Index and Immunonutritional Parameters for Postoperative Complications in Elderly Patients with Renal Cell Carcinoma |
| title_short | A Comparison of the Predictive Role of the Geriatric Nutritional Risk Index and Immunonutritional Parameters for Postoperative Complications in Elderly Patients with Renal Cell Carcinoma |
| title_sort | comparison of the predictive role of the geriatric nutritional risk index and immunonutritional parameters for postoperative complications in elderly patients with renal cell carcinoma |
| topic | geriatric nutritional risk index platelet-lymphocyte ratio postoperative complication renal cell carcinoma |
| url | http://dx.doi.org/10.1080/08941939.2020.1762808 |
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