Modeling-based Approach Towards Quality by Design for a Telescoped Process

Modeling-based Approach Towards Quality by Design for a Telescoped Process

A telescoped, two-step synthesis was investigated by applying Quality by Design principles. A kinetic model consisting of 12 individual reactions was successfully established to describe the synthesis and side reactions. The resulting model predicts the effects of changes in process parameters on to...

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Bibliographic Details
Main Authors:	This Zahnd, Maja Kandziora, Michael K. Levis, Andreas Zogg
Format:	Article
Language:	deu
Published:	Swiss Chemical Society 2024-03-01
Series:	CHIMIA
Subjects:	Continuous process improvement Kinetic modeling Quality by design (QbD)
Online Access:	https://www.chimia.ch/chimia/article/view/7202

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