Reactive Oxygen Species Interact With NLRP3 Inflammasomes and Are Involved in the Inflammation of Sepsis: From Mechanism to Treatment of Progression

Reactive Oxygen Species Interact With NLRP3 Inflammasomes and Are Involved in the Inflammation of Sepsis: From Mechanism to Treatment of Progression

Over the past 10 years, the crisis of sepsis has remained a great challenge. According to data from 2016, the sepsis-related mortality rate remains high. In addition, sepsis consumes extensive medical resources in intensive care units, and anti-inflammatory agents fail to improve sepsis-associated h...

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Bibliographic Details
Main Authors: Shuai Zhao, Fan Chen, Qiliang Yin, Dunwei Wang, Wei Han, Yuan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Physiology
Subjects:
reactive oxygen species
inflammasome
sepsis
mitochondria
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.571810/full

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