Role of G Protein-Coupled Receptors in Microglial Activation: Implication in Parkinson’s Disease

Role of G Protein-Coupled Receptors in Microglial Activation: Implication in Parkinson’s Disease

Parkinson’s disease (PD) is one of the prevalent neurodegenerative diseases associated with preferential loss of dopaminergic (DA) neurons in the substantia nigra compacta (SNc) and accumulation of α-synuclein in DA neurons. Even though the precise pathogenesis of PD is not clear, a large number of...

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Bibliographic Details
Main Authors:	Chao Gu, Yajing Chen, Yan Chen, Chun-Feng Liu, Zengyan Zhu, Mei Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-11-01
Series:	Frontiers in Aging Neuroscience
Subjects:	G protein-coupled receptor (GPCR) microglial activation Parkinson’s disease neuroinflammation dopaminergic (DA) neuronal loss
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2021.768156/full

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