Conformational dynamics as an intrinsic determinant of prion protein misfolding and neurotoxicity

Conformational dynamics as an intrinsic determinant of prion protein misfolding and neurotoxicity

Bibliographic Details
Main Authors:	Alessandro Cembran, Pedro Fernandez-Funez
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2024-01-01
Series:	Neural Regeneration Research
Online Access:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=10;spage=2095;epage=2096;aulast=

Similar Items

Prion Protein Misfolding, Strains, and Neurotoxicity: An Update from Studies on Mammalian Prions
by: Ilaria Poggiolini, et al.
Published: (2013-01-01)

Recombinant Mammalian Prions: The “Correctly” Misfolded Prion Protein Conformers
by: Jiyan Ma, et al.
Published: (2022-08-01)

Identification of Misfolded Proteins in Body Fluids for the Diagnosis of Prion Diseases
by: Francesca Properzi, et al.
Published: (2013-01-01)

Differential Accumulation of Misfolded Prion Strains in Natural Hosts of Prion Diseases
by: Zoe J. Lambert, et al.
Published: (2021-12-01)

Viroids, Satellite RNAs and Prions: Folding of Nucleic Acids and Misfolding of Proteins
by: Gerhard Steger, et al.
Published: (2024-02-01)

Screening of Anti-Prion Compounds Using the Protein Misfolding Cyclic Amplification Technology
by: Sandra Pritzkow, et al.
Published: (2024-09-01)

Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions.
by: Miguel Ángel Pérez-Castro, et al.
Published: (2025-01-01)

A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions
by: Hasier Eraña, et al.
Published: (2024-03-01)

Alteration of Biomolecular Conformation by Aluminum-Implications for Protein Misfolding Disease
by: Yuhai Zhao, et al.
Published: (2022-08-01)

Dysbiosis of the gut microbiota and its effect on α-synuclein and prion protein misfolding: consequences for neurodegeneration
by: Nasir Uddin Mahbub, et al.
Published: (2024-02-01)

Highly infectious prions are not directly neurotoxic
by: Benilova, Iryna, et al.
Published: (2020)

Protein misfolding, aggregation and conformational diseases : Part B Molecular mechanisms of conformational diseases /
by: Uversky, Vladimir N., et al.
Published: (2007)

Protein misfolding /
by: O'Doherty, Cian B., et al.
Published: (c200)

Investigation on the conformational conversion of human prion protein by molecular dynamics simulation
by: Yang, Hong
Published: (2017)

Inter- and intra-species conversion efficacies of Norwegian prion isolates estimated by serial protein misfolding cyclic amplification
by: Erez Harpaz, et al.
Published: (2023-09-01)

Evidence of Orientation-Dependent Early States of Prion Protein Misfolded Structures from Single Molecule Force Spectroscopy
by: Andrea Raspadori, et al.
Published: (2022-09-01)

Role of Protein Misfolding and Proteostasis Deficiency in Protein Misfolding Diseases and Aging
by: Karina Cuanalo-Contreras, et al.
Published: (2013-01-01)

Structural determinants of conformationally selective, prion-binding aptamers.
by: Sayer, N, et al.
Published: (2004)

Conformational Enigma of TDP-43 Misfolding in Neurodegenerative Disorders
by: Meenakshi Pillai, et al.
Published: (2024-09-01)

Recent Advances in Our Molecular and Mechanistic Understanding of Misfolded Cellular Proteins in Alzheimer’s Disease (AD) and Prion Disease (PrD)
by: Walter J. Lukiw
Published: (2022-01-01)

Protein Misfolding and Human Disease
by: Christopher Dobson
Published: (2002-01-01)

Protein Misfolding and Neurodegenerative Diseases
by: Alessio Cardinale, et al.
Published: (2014-01-01)

New MAPS for misfolded proteins
by: Christianson, J, et al.
Published: (2016)

Pressure reveals unique conformational features in prion protein fibril diversity
by: Torrent, J, et al.
Published: (2019)

Misfolded protein oligomers: mechanisms of formation, cytotoxic effects, and pharmacological approaches against protein misfolding diseases
by: Dillon J. Rinauro, et al.
Published: (2024-02-01)

Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered Proteins
by: Halfmann, Randal Arthur, et al.
Published: (2014)

Protein folding and misfolding : neurodegenerative diseases /
by: Ovadi, Judit, et al.
Published: (2009)

Misfolded amyloid-beta conformational variants (strains) as drivers of Alzheimer’s disease neuropathology
by: Salvatore Saieva, et al.
Published: (2025-11-01)

Prion infections and anti-PrP antibodies trigger converging neurotoxic pathways.
by: Uli S Herrmann, et al.
Published: (2015-02-01)

The Role of Protein S-Nitrosylation in Protein Misfolding-Associated Diseases
by: Yun-Jin Ju, et al.
Published: (2021-07-01)

Visualizing single-molecule conformational transition and binding dynamics of intrinsically disordered proteins
by: Wenzhe Liu, et al.
Published: (2023-08-01)

Misfolded protein? we have a chemical for that
Published: (2014-05-01)

Metabolic regulation of misfolded protein import into mitochondria
by: Yuhao Wang, et al.
Published: (2024-06-01)

Proteostasis Response to Protein Misfolding in Controlled Hypertension
by: Manuel Teixeira, et al.
Published: (2022-05-01)

Protein folding and misfolding : relevance to biotechnology and medicine /
by: 178195 Saad Tayyab
Published: (2011)

The cellular prion protein beyond prion diseases
by: Giorgia Manni, et al.
Published: (2020-04-01)

Conformational pH dependence of intermediate states during oligomerization of the human prion protein.
by: Gerber, R, et al.
Published: (2008)

The impact of membrane composition on conformation and trafficking of lipidated prion protein (PrP) variants
by: Hackl, Stefanie
Published: (2020)

The impact of membrane composition on conformation and trafficking of lipidated prion protein (PrP) variants
by: Hackl, Stefanie
Published: (2020)

Physiological Metals Can Induce Conformational Changes in Transthyretin Structure: Neuroprotection or Misfolding Induction?
by: Lidia Ciccone, et al.
Published: (2021-03-01)