Design, synthesis and evaluation of novel dehydroabietic acid-dithiocarbamate hybrids as potential multi-targeted compounds for tumor cytotoxicity

Design, synthesis and evaluation of novel dehydroabietic acid-dithiocarbamate hybrids as potential multi-targeted compounds for tumor cytotoxicity

In the present study, novel representatives of the important group of biologically-active, dehydroabietic acid-bearing dithiocarbamate moiety, were synthesized and characterized by 1H NMR, 13C NMR, HR-MS. The in vitro antiproliferative activity evaluation (MTT) indicated that these compounds exhibit...

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Bibliographic Details
Main Authors:	Chengyang Ni, YaJu Wu, Mei Ran, Jingyan Li, Hong Li, Cai Lan, Jian Liu, Ping Dai, Jianming Wu, Fangyao Li
Format:	Article
Language:	English
Published:	Elsevier 2022-10-01
Series:	Arabian Journal of Chemistry
Subjects:	Dehydroabietic Acid Dithiocarbamate Synthesis Antitumor activity Molecular docking
Online Access:	http://www.sciencedirect.com/science/article/pii/S1878535222004610

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