Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit

Objective:This study aimed to determine the factors affecting the mortality of patients in critical condition with coronavirus disease-2019 (COVID-19) in the intensive care unit (ICU).Materials and Methods:We included a total of 445 patients who are admitted in the ICU due to COVID-19. Patients were...

Full description

Bibliographic Details
Main Authors: Osman Uzundere, Cem Kıvılcım Kaçar, Meral Erdal Erbatur, Mehmet Salih Gül, Mesut Akgündüz, Zeki Korhan, Ömer Can
Format: Article
Language:English
Published: Galenos Yayinevi 2021-12-01
Series:Türk Yoğun Bakim Derneği Dergisi
Subjects:
Online Access: http://www.turkishjic.org/archives/archive-detail/article-preview/factors-affecting-the-mortality-of-patients-in-cri/47553
_version_ 1797912733257039872
author Osman Uzundere
Cem Kıvılcım Kaçar
Meral Erdal Erbatur
Mehmet Salih Gül
Mesut Akgündüz
Zeki Korhan
Ömer Can
author_facet Osman Uzundere
Cem Kıvılcım Kaçar
Meral Erdal Erbatur
Mehmet Salih Gül
Mesut Akgündüz
Zeki Korhan
Ömer Can
author_sort Osman Uzundere
collection DOAJ
description Objective:This study aimed to determine the factors affecting the mortality of patients in critical condition with coronavirus disease-2019 (COVID-19) in the intensive care unit (ICU).Materials and Methods:We included a total of 445 patients who are admitted in the ICU due to COVID-19. Patients were divided into two groups-those who survived and those who died during the ICU follow-up-and their demographic, clinical and laboratory characteristics were compared. Factors affecting mortality were also determined.Results:Older age, high Kidney Disease: Improving Global Outcome (KDIGO) stage and Sequential Organ Failure Assessment (SOFA) scores at first admission to the ICU, high neutrophil/lymphocyte ratio, high D-dimer levels, low bicarbonate (HCO3) values and high lactate dehydrogenase (LDH) and creatinine levels were determined as independent risk factors for mortality in patients in critical condition with COVID-19 admitted in the ICU. Particularly, a substantial relationship was observed between the KDIGO stage and mortality during the ICU admission.Conclusion:Age, KDIGO stage and SOFA scores at first admission, neutrophil/lymphocyte ratio and D-dimer, HCO3, LDH and creatinine levels were independent risk factors for mortality in patients in critical condition with COVID-19 admitted in the ICU.
first_indexed 2024-04-10T12:00:41Z
format Article
id doaj.art-bc3b7a1dcb314f0a954ee662560eed7c
institution Directory Open Access Journal
issn 2146-6416
2147-267X
language English
last_indexed 2024-04-10T12:00:41Z
publishDate 2021-12-01
publisher Galenos Yayinevi
record_format Article
series Türk Yoğun Bakim Derneği Dergisi
spelling doaj.art-bc3b7a1dcb314f0a954ee662560eed7c2023-02-15T16:16:37ZengGalenos YayineviTürk Yoğun Bakim Derneği Dergisi2146-64162147-267X2021-12-01191546110.4274/tybd.galenos.2021.2008213049054Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care UnitOsman Uzundere0Cem Kıvılcım Kaçar1Meral Erdal Erbatur2Mehmet Salih Gül3Mesut Akgündüz4Zeki Korhan5Ömer Can6 University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey Objective:This study aimed to determine the factors affecting the mortality of patients in critical condition with coronavirus disease-2019 (COVID-19) in the intensive care unit (ICU).Materials and Methods:We included a total of 445 patients who are admitted in the ICU due to COVID-19. Patients were divided into two groups-those who survived and those who died during the ICU follow-up-and their demographic, clinical and laboratory characteristics were compared. Factors affecting mortality were also determined.Results:Older age, high Kidney Disease: Improving Global Outcome (KDIGO) stage and Sequential Organ Failure Assessment (SOFA) scores at first admission to the ICU, high neutrophil/lymphocyte ratio, high D-dimer levels, low bicarbonate (HCO3) values and high lactate dehydrogenase (LDH) and creatinine levels were determined as independent risk factors for mortality in patients in critical condition with COVID-19 admitted in the ICU. Particularly, a substantial relationship was observed between the KDIGO stage and mortality during the ICU admission.Conclusion:Age, KDIGO stage and SOFA scores at first admission, neutrophil/lymphocyte ratio and D-dimer, HCO3, LDH and creatinine levels were independent risk factors for mortality in patients in critical condition with COVID-19 admitted in the ICU. http://www.turkishjic.org/archives/archive-detail/article-preview/factors-affecting-the-mortality-of-patients-in-cri/47553 coronavirus disease 2019icukidney disease: improving global outcomemortalitysequential organ failure assessment score
spellingShingle Osman Uzundere
Cem Kıvılcım Kaçar
Meral Erdal Erbatur
Mehmet Salih Gül
Mesut Akgündüz
Zeki Korhan
Ömer Can
Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit
Türk Yoğun Bakim Derneği Dergisi
coronavirus disease 2019
icu
kidney disease: improving global outcome
mortality
sequential organ failure assessment score
title Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit
title_full Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit
title_fullStr Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit
title_full_unstemmed Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit
title_short Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit
title_sort factors affecting the mortality of patients in critical condition with coronavirus disease 2019 in the intensive care unit
topic coronavirus disease 2019
icu
kidney disease: improving global outcome
mortality
sequential organ failure assessment score
url http://www.turkishjic.org/archives/archive-detail/article-preview/factors-affecting-the-mortality-of-patients-in-cri/47553
work_keys_str_mv AT osmanuzundere factorsaffectingthemortalityofpatientsincriticalconditionwithcoronavirusdisease2019intheintensivecareunit
AT cemkıvılcımkacar factorsaffectingthemortalityofpatientsincriticalconditionwithcoronavirusdisease2019intheintensivecareunit
AT meralerdalerbatur factorsaffectingthemortalityofpatientsincriticalconditionwithcoronavirusdisease2019intheintensivecareunit
AT mehmetsalihgul factorsaffectingthemortalityofpatientsincriticalconditionwithcoronavirusdisease2019intheintensivecareunit
AT mesutakgunduz factorsaffectingthemortalityofpatientsincriticalconditionwithcoronavirusdisease2019intheintensivecareunit
AT zekikorhan factorsaffectingthemortalityofpatientsincriticalconditionwithcoronavirusdisease2019intheintensivecareunit
AT omercan factorsaffectingthemortalityofpatientsincriticalconditionwithcoronavirusdisease2019intheintensivecareunit