Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit
Objective:This study aimed to determine the factors affecting the mortality of patients in critical condition with coronavirus disease-2019 (COVID-19) in the intensive care unit (ICU).Materials and Methods:We included a total of 445 patients who are admitted in the ICU due to COVID-19. Patients were...
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Format: | Article |
Language: | English |
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Galenos Yayinevi
2021-12-01
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Series: | Türk Yoğun Bakim Derneği Dergisi |
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http://www.turkishjic.org/archives/archive-detail/article-preview/factors-affecting-the-mortality-of-patients-in-cri/47553
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author | Osman Uzundere Cem Kıvılcım Kaçar Meral Erdal Erbatur Mehmet Salih Gül Mesut Akgündüz Zeki Korhan Ömer Can |
author_facet | Osman Uzundere Cem Kıvılcım Kaçar Meral Erdal Erbatur Mehmet Salih Gül Mesut Akgündüz Zeki Korhan Ömer Can |
author_sort | Osman Uzundere |
collection | DOAJ |
description | Objective:This study aimed to determine the factors affecting the mortality of patients in critical condition with coronavirus disease-2019 (COVID-19) in the intensive care unit (ICU).Materials and Methods:We included a total of 445 patients who are admitted in the ICU due to COVID-19. Patients were divided into two groups-those who survived and those who died during the ICU follow-up-and their demographic, clinical and laboratory characteristics were compared. Factors affecting mortality were also determined.Results:Older age, high Kidney Disease: Improving Global Outcome (KDIGO) stage and Sequential Organ Failure Assessment (SOFA) scores at first admission to the ICU, high neutrophil/lymphocyte ratio, high D-dimer levels, low bicarbonate (HCO3) values and high lactate dehydrogenase (LDH) and creatinine levels were determined as independent risk factors for mortality in patients in critical condition with COVID-19 admitted in the ICU. Particularly, a substantial relationship was observed between the KDIGO stage and mortality during the ICU admission.Conclusion:Age, KDIGO stage and SOFA scores at first admission, neutrophil/lymphocyte ratio and D-dimer, HCO3, LDH and creatinine levels were independent risk factors for mortality in patients in critical condition with COVID-19 admitted in the ICU. |
first_indexed | 2024-04-10T12:00:41Z |
format | Article |
id | doaj.art-bc3b7a1dcb314f0a954ee662560eed7c |
institution | Directory Open Access Journal |
issn | 2146-6416 2147-267X |
language | English |
last_indexed | 2024-04-10T12:00:41Z |
publishDate | 2021-12-01 |
publisher | Galenos Yayinevi |
record_format | Article |
series | Türk Yoğun Bakim Derneği Dergisi |
spelling | doaj.art-bc3b7a1dcb314f0a954ee662560eed7c2023-02-15T16:16:37ZengGalenos YayineviTürk Yoğun Bakim Derneği Dergisi2146-64162147-267X2021-12-01191546110.4274/tybd.galenos.2021.2008213049054Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care UnitOsman Uzundere0Cem Kıvılcım Kaçar1Meral Erdal Erbatur2Mehmet Salih Gül3Mesut Akgündüz4Zeki Korhan5Ömer Can6 University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey University of Health Sciences Turkey, Diyarbakır Gazi Yaşargil Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Diyarbakır, Turkey Objective:This study aimed to determine the factors affecting the mortality of patients in critical condition with coronavirus disease-2019 (COVID-19) in the intensive care unit (ICU).Materials and Methods:We included a total of 445 patients who are admitted in the ICU due to COVID-19. Patients were divided into two groups-those who survived and those who died during the ICU follow-up-and their demographic, clinical and laboratory characteristics were compared. Factors affecting mortality were also determined.Results:Older age, high Kidney Disease: Improving Global Outcome (KDIGO) stage and Sequential Organ Failure Assessment (SOFA) scores at first admission to the ICU, high neutrophil/lymphocyte ratio, high D-dimer levels, low bicarbonate (HCO3) values and high lactate dehydrogenase (LDH) and creatinine levels were determined as independent risk factors for mortality in patients in critical condition with COVID-19 admitted in the ICU. Particularly, a substantial relationship was observed between the KDIGO stage and mortality during the ICU admission.Conclusion:Age, KDIGO stage and SOFA scores at first admission, neutrophil/lymphocyte ratio and D-dimer, HCO3, LDH and creatinine levels were independent risk factors for mortality in patients in critical condition with COVID-19 admitted in the ICU. http://www.turkishjic.org/archives/archive-detail/article-preview/factors-affecting-the-mortality-of-patients-in-cri/47553 coronavirus disease 2019icukidney disease: improving global outcomemortalitysequential organ failure assessment score |
spellingShingle | Osman Uzundere Cem Kıvılcım Kaçar Meral Erdal Erbatur Mehmet Salih Gül Mesut Akgündüz Zeki Korhan Ömer Can Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit Türk Yoğun Bakim Derneği Dergisi coronavirus disease 2019 icu kidney disease: improving global outcome mortality sequential organ failure assessment score |
title | Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit |
title_full | Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit |
title_fullStr | Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit |
title_full_unstemmed | Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit |
title_short | Factors Affecting the Mortality of Patients in Critical Condition with Coronavirus Disease-2019 in the Intensive Care Unit |
title_sort | factors affecting the mortality of patients in critical condition with coronavirus disease 2019 in the intensive care unit |
topic | coronavirus disease 2019 icu kidney disease: improving global outcome mortality sequential organ failure assessment score |
url |
http://www.turkishjic.org/archives/archive-detail/article-preview/factors-affecting-the-mortality-of-patients-in-cri/47553
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