PVA-Microbubbles as a Radioembolization Platform: Formulation and the In Vitro Proof of Concept

PVA-Microbubbles as a Radioembolization Platform: Formulation and the In Vitro Proof of Concept

This proof-of-concept study lays the foundations for the development of a delivery strategy for radioactive lanthanides, such as Yttrium-90, against recurrent glioblastoma. Our appealing hypothesis is that by taking advantage of the combination of biocompatible polyvinyl alcohol (PVA) microbubbles (...

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Bibliographic Details
Main Authors: Valerio Da Ros, Letizia Oddo, Yosra Toumia, Eugenia Guida, Silvia Minosse, Lidia Strigari, Silvia Strolin, Giulia Paolani, Francesca Di Giuliano, Roberto Floris, Francesco Garaci, Susanna Dolci, Gaio Paradossi, Fabio Domenici
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
PVA microbubbles
glioblastoma
radioembolization
yttrium
DOTA
RGD
Online Access:https://www.mdpi.com/1999-4923/15/1/217

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